Martin H. Wühr
Icahn Laboratory, 246
Develop and employ quantitative proteomics methods to obtain a systems level understanding of cellular organization
The Wühr Lab is located in the Lewis-Sigler Institute at Princeton University. We aim to elucidate principles by which molecules self-organize into much larger organelles and cells. Specifically, we study how proteins partition between nucleus and cytoplasm and how different nuclear composition affects cellular function. To address these questions, we develop and employ quantitative proteomics in combination with computational, biochemical and imaging approaches.