Publications
Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts. Science. 2021 ;371(6532).
. Cell position fates and collective fountain flow in bacterial biofilms revealed by light-sheet microscopy. Science. 2020 ;369(6499):71-77.
. Hierarchical transitions and fractal wrinkling drive bacterial pellicle morphogenesis. Proc Natl Acad Sci U S A. 2021 ;118(20).
. Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials. Crit Care. 2022 ;26(1):128.
. Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm. Nat Commun. 2019 ;10(1):2320.
. Structural basis for catalysis and substrate specificity of human ACAT1. Nature. 2020 ;581(7808):333-338.
. Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2. Cell. 2020 ;182(1):98-111.e18.
. Structure of the Human Lipid Exporter ABCA1. Cell. 2017 ;169(7):1228-1239.e10.
. Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4. Cell. 2010 ;141(3):446-57.
.