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2021
DeCandia AL, Schrom EC, Brandell EE, Stahler DR, vonHoldt BM. Sarcoptic mange severity is associated with reduced genomic variation and evidence of selection in Yellowstone National Park wolves (). Evol Appl. 2021 ;14(2):429-445.
Sanders DW, Jumper CC, Ackerman PJ, Bracha D, Donlic A, Kim H, et al. SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation. Elife. 2021 ;10.
Verma A, Jena SG, Isakov DR, Aoki K, Toettcher JE, Engelhardt BE. A self-exciting point process to study multicellular spatial signaling patterns. Proc Natl Acad Sci U S A. 2021 ;118(32).
Shi C, Murphy CT. Sex and death. Curr Top Dev Biol. 2021 ;144:353-375.
García-Cañaveras JC, Lancho O, Ducker GS, Ghergurovich JM, Xu X, da Silva-Diz V, et al.. SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia. Leukemia. 2021 ;35(2):377-388.
Farahani PE, Reed EH, Underhill EJ, Aoki K, Toettcher JE. Signaling, Deconstructed: Using Optogenetics to Dissect and Direct Information Flow in Biological Systems. Annu Rev Biomed Eng. 2021 ;23:61-87.
Ruf-Zamojski F, Zhang Z, Zamojski M, Smith GR, Mendelev N, Liu H, et al. Single nucleus multi-omics regulatory landscape of the murine pituitary. Nat Commun. 2021 ;12(1):2677.
Quinn JJ, Jones MG, Okimoto RA, Nanjo S, Chan MM, Yosef N, et al. Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts. Science. 2021 ;371(6532).
Diegmiller R, Doherty CA, Stern T, Alsous JImran, Shvartsman SY. Size scaling in collective cell growth. Development. 2021 ;148(18).
Taron UH, Salado I, Escobar-Rodríguez M, Westbury MV, Butschkau S, Paijmans JLA, et al.. A sliver of the past: The decimation of the genetic diversity of the Mexican wolf. Mol Ecol. 2021 ;.
DeCandia AL, Cassidy KA, Stahler DR, Stahler EA, vonHoldt BM. Social environment and genetics underlie body site-specific microbiomes of Yellowstone National Park gray wolves (). Ecol Evol. 2021 ;11(14):9472-9488.
TeSlaa T, Bartman CR, Jankowski CSR, Zhang Z, Xu X, Xing X, et al. The Source of Glycolytic Intermediates in Mammalian Tissues. Cell Metab. 2021 ;33(2):367-378.e5.
Huang S-K, Whitney PH, Dutta S, Shvartsman SY, Rushlow CA. Spatial organization of transcribing loci during early genome activation in Drosophila. Curr Biol. 2021 ;.
Lindström NO, Sealfon R, Chen X, Parvez RK, Ransick A, Brandine GDe Sena, et al.. Spatial transcriptional mapping of the human nephrogenic program. Dev Cell. 2021 ;56(16):2381-2398.e6.
Bird LM, Ochoa-Lubinoff C, Tan W-H, Heimer G, Melmed RD, Rakhit A, et al. The STARS Phase 2 Study: A Randomized Controlled Trial of Gaboxadol in Angelman Syndrome. Neurology. 2021 ;96(7):e1024-e1035.
Li Z, Jin X, Wu T, Huang G, Wu K, Lei J, et al. Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Na 1.5 by the Antiarrhythmic Drug Quinidine*. Angew Chem Int Ed Engl. 2021 ;60(20):11474-11480.
Yan R, Cao P, Song W, Li Y, Wang T, Qian H, et al. Structural basis for sterol sensing by Scap and Insig. Cell Rep. 2021 ;35(13):109299.
Gong D, Yan N, Ledford HA. Structural Basis for the Modulation of Ryanodine Receptors. Trends Biochem Sci. 2021 ;46(6):489-501.
Gao S, Yan N. Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Ca 1.1 by Dihydropyridine Compounds*. Angew Chem Int Ed Engl. 2021 ;60(6):3131-3137.
Shen H, Yan N, Pan X. Structural determination of human Na v 1.4 and Na v 1.7 using single particle cryo-electron microscopy. Methods Enzymol. 2021 ;653:103-120.
Velthuis AJWTe, Grimes JM, Fodor E. Structural insights into RNA polymerases of negative-sense RNA viruses. Nat Rev Microbiol. 2021 ;19(5):303-318.
Sochacki KA, Heine BL, Haber GJ, Jimah JR, Prasai B, Alfonzo-Méndez MA, et al.. The structure and spontaneous curvature of clathrin lattices at the plasma membrane. Dev Cell. 2021 ;56(8):1131-1146.e3.
Gao S, Yao X, Yan N. Structure of human Ca2.2 channel blocked by the painkiller ziconotide. Nature. 2021 ;596(7870):143-147.
Li Z, Jin X, Wu T, Zhao X, Wang W, Lei J, et al. Structure of human Na1.5 reveals the fast inactivation-related segments as a mutational hotspot for the long QT syndrome. Proc Natl Acad Sci U S A. 2021 ;118(11).
Yan R, Cao P, Song W, Qian H, Du X, Coates HW, et al. A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols. Science. 2021 ;371(6533).