Publications
Structure and mechanism of human diacylglycerol O-acyltransferase 1. Nature. 2020 ;581(7808):329-332.
. Structure and mechanism of the uracil transporter UraA. Nature. 2011 ;472(7342):243-6.
. The structure and precision of retinal spike trains. Proc Natl Acad Sci U S A. 1997 ;94(10):5411-6.
. The structure and spontaneous curvature of clathrin lattices at the plasma membrane. Dev Cell. 2021 ;56(8):1131-1146.e3.
. Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution. Science. 2017 ;355(6328).
. Structure of a fucose transporter in an outward-open conformation. Nature. 2010 ;467(7316):734-8.
. Structure of human Ca2.2 channel blocked by the painkiller ziconotide. Nature. 2021 ;596(7870):143-147.
. Structure of human Na1.5 reveals the fast inactivation-related segments as a mutational hotspot for the long QT syndrome. Proc Natl Acad Sci U S A. 2021 ;118(11).
. Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria. Proc Natl Acad Sci U S A. 2022 ;119(26):e2200923119.
. Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response. Science. 2014 ;343(6176):1244-8.
. A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols. Science. 2021 ;371(6533).
. Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel. Nature. 2009 ;462(7272):467-72.
. Structure of the Human Lipid Exporter ABCA1. Cell. 2017 ;169(7):1228-1239.e10.
. Structure of the human voltage-gated sodium channel Na1.4 in complex with β1. Science. 2018 ;362(6412).
. Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates. J Am Chem Soc. 2016 ;138(50):16452-16458.
. Structure of the Na1.4-β1 Complex from Electric Eel. Cell. 2017 ;170(3):470-482.e11.
. Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution. Nature. 2015 ;517(7532):50-55.
. Structure of the voltage-gated calcium channel Cav1.1 complex. Science. 2015 ;350(6267):aad2395.
. Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition. Cell Res. 2015 ;25(4):401-11.
. Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. PLoS Biol. 2016 ;14(5):e1002464.
. Structure-activity relationships for a series of compounds that inhibit aggregation of the Alzheimer's peptide, Aβ42. Chem Biol Drug Des. 2014 ;84(5):505-12.
. Structure-based assessment of disease-related mutations in human voltage-gated sodium channels. Protein Cell. 2017 ;8(6):401-438.
. Structure-Based Design, Optimization, and Evaluation of Potent Stabilized Peptide Inhibitors Disrupting MTDH and SND1 Interaction. J Med Chem. 2022 ;65(18):12188-12199.
. Structured Chart Review: Assessment of a Structured Chart Review Methodology. Hosp Pediatr. 2020 ;10(1):61-69.
. Structured foraging of soil predators unveils functional responses to bacterial defenses. Proc Natl Acad Sci U S A. 2022 ;119(52):e2210995119.
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