Publications
Chaperoning SNARE Folding and Assembly. Annu Rev Biochem. 2021 ;90:581-603.
. A multifaceted signal recorder of cellular experiences using Cas12a base-editing. Trends Biotechnol. 2022 ;40(11):1279-1281.
. Enhancing CD8 T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 2017 ;32(3):377-391.e9.
. Traditional and novel tools to probe the mitochondrial metabolism in health and disease. Wiley Interdiscip Rev Syst Biol Med. 2017 ;9(2).
. Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein. Nat Cell Biol. 2020 ;22(6):674-688.
. A Metabolic Engineering Approach to Incorporate Modified Pyrimidine Nucleosides into Cellular RNA. J Am Chem Soc. 2019 ;141(8):3347-3351.
. RNA Controls PolyQ Protein Phase Transitions. Mol Cell. 2015 ;60(2):220-30.
. Discovery of a Cryptic Depsipeptide from Streptomyces ghanaensis via MALDI-MS-Guided High-Throughput Elicitor Screening. Angew Chem Int Ed Engl. 2020 ;59(51):23005-23009.
. Biosensor for branched-chain amino acid metabolism in yeast and applications in isobutanol and isopentanol production. Nat Commun. 2022 ;13(1):270.
. Mechanical Frustration of Phase Separation in the Cell Nucleus by Chromatin. Phys Rev Lett. 2021 ;126(25):258102.
. Global and gene-specific translational regulation in Escherichia coli across different conditions. PLoS Comput Biol. 2022 ;18(10):e1010641.
. CanE, an Iron/2-Oxoglutarate-Dependent Lasso Peptide Hydroxylase from . ACS Chem Biol. 2020 ;15(4):890-894.
. G6PD-mediated increase in de novo NADP biosynthesis promotes antioxidant defense and tumor metastasis. Sci Adv. 2022 ;8(29):eabo0404.
. Single nucleus transcriptome and chromatin accessibility of postmortem human pituitaries reveal diverse stem cell regulatory mechanisms. Cell Rep. 2022 ;38(10):110467.
. Analysis of the selectivity filter of the voltage-gated sodium channel Na(v)Rh. Cell Res. 2013 ;23(3):409-22.
. Chemical Basis for Deuterium Labeling of Fat and NADPH. J Am Chem Soc. 2017 ;139(41):14368-14371.
. Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout. Proc Natl Acad Sci U S A. 2021 ;118(6).
. Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca Channel. Cell. 2019 ;177(6):1495-1506.e12.
. Development of a pan-neuronal genetic driver in mosquitoes. Cell Rep Methods. 2021 ;1(3).
. The CD44s splice isoform is a central mediator for invadopodia activity. J Cell Sci. 2016 ;129(7):1355-65.
. Design and Characterization of Rapid Optogenetic Circuits for Dynamic Control in Yeast Metabolic Engineering. ACS Synth Biol. 2020 ;9(12):3254-3266.
. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 2020 ;579(7800):586-591.
. Myeloid-derived itaconate suppresses cytotoxic CD8 T cells and promotes tumour growth. Nat Metab. 2022 ;4(12):1660-1673.
. Liquid Imbibition in Ceramic-Coated Carbon Nanotube Films. Langmuir. 2016 ;32(48):12686-12692.
. Cryo-EM structures of apo and antagonist-bound human Ca3.1. Nature. 2019 ;576(7787):492-497.
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