Publications
Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate. Proc Natl Acad Sci U S A. 2022 ;119(11):e2112008119.
. Regulation of Virulence in Staphylococcus aureus: Molecular Mechanisms and Remaining Puzzles. Cell Chem Biol. 2016 ;23(2):214-224.
. Structure and mechanism of human diacylglycerol O-acyltransferase 1. Nature. 2020 ;581(7808):329-332.
. A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate. Cell Metab. 2019 ;30(1):174-189.e5.
. Isolation disrupts social interactions and destabilizes brain development in bumblebees. Curr Biol. 2022 ;32(12):2754-2764.e5.
. Live-Cell RNA Imaging with Metabolically Incorporated Fluorescent Nucleosides. J Am Chem Soc. 2022 ;144(32):14647-14656.
. Functional Plasticity of the AgrC Receptor Histidine Kinase Required for Staphylococcal Virulence. Cell Chem Biol. 2017 ;24(1):76-86.
. Investigation of the Genetics and Biochemistry of Roseobacticide Production in the Roseobacter Clade Bacterium Phaeobacter inhibens. mBio. 2016 ;7(2):e02118.
. Revealing evolutionary constraints on proteins through sequence analysis. PLoS Comput Biol. 2019 ;15(4):e1007010.
. Spatially resolved isotope tracing reveals tissue metabolic activity. Nat Methods. 2022 ;19(2):223-230.
. Molecular basis for inhibiting human glucose transporters by exofacial inhibitors. Nat Commun. 2022 ;13(1):2632.
. Physics meets biology: The joining of two forces to further our understanding of cellular function. Mol Cell. 2021 ;81(15):3033-3037.
. Algal p-coumaric acid induces oxidative stress and siderophore biosynthesis in the bacterial symbiont Phaeobacter inhibens. Cell Chem Biol. 2022 ;29(4):670-679.e5.
. Cell- and Polymerase-Selective Metabolic Labeling of Cellular RNA with 2'-Azidocytidine. J Am Chem Soc. 2020 ;142(34):14417-14421.
. Key driving forces in the biosynthesis of autoinducing peptides required for staphylococcal virulence. Proc Natl Acad Sci U S A. 2015 ;112(34):10679-84.
. Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel. Nature. 2009 ;462(7272):467-72.
. The PSI-U1 snRNP interaction regulates male mating behavior in Drosophila. Proc Natl Acad Sci U S A. 2016 ;113(19):5269-74.
. Crystal structure of a bacterial homologue of SWEET transporters. Cell Res. 2014 ;24(12):1486-9.
. Quorum sensing: cell-to-cell communication in bacteria. Annu Rev Cell Dev Biol. 2005 ;21:319-46.
. Control of the type 3 secretion system in Vibrio harveyi by quorum sensing through repression of ExsA. Appl Environ Microbiol. 2010 ;76(15):4996-5004.
. Quorum sensing controls biofilm formation in Vibrio cholerae through modulation of cyclic di-GMP levels and repression of vpsT. J Bacteriol. 2008 ;190(7):2527-36.
. Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans. Elife. 2016 ;5.
. ERK signaling dissolves ERF repression condensates in living embryos. Proc Natl Acad Sci U S A. 2022 ;119(9).
. Telomere les(i/s)ons from a telomerase RNA mutant. Cell Cycle. 2015 ;14(24):3769-70.
. Telomerase RNA is more than a DNA template. RNA Biol. 2016 ;13(8):683-9.
.