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2020
Wan L, Chong S, Xuan F, Liang A, Cui X, Gates L, et al. Impaired cell fate through gain-of-function mutations in a chromatin reader. Nature. 2020 ;577(7788):121-126.
Hermans D, Gautam S, García-Cañaveras JC, Gromer D, Mitra S, Spolski R, et al.. Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8 T cell stemness and antitumor immunity. Proc Natl Acad Sci U S A. 2020 ;117(11):6047-6055.
Goglia AG, Wilson MZ, Jena SG, Silbert J, Basta LP, Devenport D, et al. A Live-Cell Screen for Altered Erk Dynamics Reveals Principles of Proliferative Control. Cell Syst. 2020 ;10(3):240-253.e6.
Sargin D, Chottekalapanda RU, Perit KE, Yao V, Chu D, Sparks DW, et al. Mapping the physiological and molecular markers of stress and SSRI antidepressant treatment in S100a10 corticostriatal neurons. Mol Psychiatry. 2020 ;25(5):1112-1129.
Fiore VF, Krajnc M, Quiroz FGarcia, Levorse J, H Pasolli A, Shvartsman SY, et al. Mechanics of a multilayer epithelium instruct tumour architecture and function. Nature. 2020 ;585(7825):433-439.
Liou CS, Sirk SJ, Diaz CAC, Klein AP, Fischer CR, Higginbottom SK, et al. A Metabolic Pathway for Activation of Dietary Glucosinolates by a Human Gut Symbiont. Cell. 2020 ;180(4):717-728.e19.
Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, et al. Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Mol Cancer Res. 2020 ;18(4):599-611.
Laval K, Maturana CJ, Enquist LW. Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses. J Vis Exp. 2020 ;(160).
Wei M-T, Chang Y-C, Shimobayashi SF, Shin Y, Strom AR, Brangwynne CP. Nucleated transcriptional condensates amplify gene expression. Nat Cell Biol. 2020 ;22(10):1187-1196.
Gil AA, Carrasco-López C, Zhu L, Zhao EM, Ravindran PT, Wilson MZ, et al.. Optogenetic control of protein binding using light-switchable nanobodies. Nat Commun. 2020 ;11(1):4044.
Javdan B, Lopez JG, Chankhamjon P, Lee Y-CJ, Hull R, Wu Q, et al. Personalized Mapping of Drug Metabolism by the Human Gut Microbiome. Cell. 2020 ;181(7):1661-1679.e22.
Hartenian E, Gilbertson S, Federspiel JD, Cristea IM, Glaunsinger BA. RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters. PLoS Pathog. 2020 ;16(2):e1008269.
Roussarie J-P, Yao V, Rodriguez-Rodriguez P, Oughtred R, Rust J, Plautz Z, et al. Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis. Neuron. 2020 ;107(5):821-835.e12.
Ramanathan HN, Zhang S, Douam F, Mar KB, Chang J, Yang PL, et al. A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating. mBio. 2020 ;11(2).
Yang L, Canaveras JCarlos Gar, Chen Z, Wang L, Liang L, Jang C, et al. Serine Catabolism Feeds NADH when Respiration Is Impaired. Cell Metab. 2020 ;31(4):809-821.e6.
Luongo TS, Eller JM, Lu M-J, Niere M, Raith F, Perry C, et al. SLC25A51 is a mammalian mitochondrial NAD transporter. Nature. 2020 ;588(7836):174-179.
Akkina R, Barber DL, Bility MT, Bissig K-D, Burwitz BJ, Eichelberg K, et al. Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop. Curr HIV Res. 2020 ;18(1):19-28.
Jang C, Wada S, Yang S, Gosis B, Zeng X, Zhang Z, et al. The small intestine shields the liver from fructose-induced steatosis. Nat Metab. 2020 ;2(7):586-593.
Vega ME, Kastberger B, Wehrle-Haller B, Schwarzbauer JE. Stimulation of Fibronectin Matrix Assembly by Lysine Acetylation. Cells. 2020 ;9(3).
Wong C, Tang LH, Davidson C, Vosburgh E, Chen W, Foran DJ, et al. Two well-differentiated pancreatic neuroendocrine tumor mouse models. Cell Death Differ. 2020 ;27(1):269-283.
2021
Liu Y, Maya S, Ploss A. Animal Models of Hepatitis B Virus Infection-Success, Challenges, and Future Directions. Viruses. 2021 ;13(5).
Kumar S, Nandi A, Singh S, Regulapati R, Li N, Tobias JW, et al. Dll1 quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway. Nat Commun. 2021 ;12(1):432.
Song K, Cai X, Dong Y, Wu H, Wei Y, Shankavaram UT, et al. Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development. J Clin Invest. 2021 ;131(1).
Posfai E, Schell JPaul, Janiszewski A, Rovic I, Murray A, Bradshaw B, et al. Evaluating totipotency using criteria of increasing stringency. Nat Cell Biol. 2021 ;23(1):49-60.
Garrison CM, Schwarzbauer JE. Fibronectin fibril alignment is established upon initiation of extracellular matrix assembly. Mol Biol Cell. 2021 ;32(8):739-752.