Publications
Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin. Clin Cancer Res. 2017 ;23(18):5639-5647.
. Phase Transitioning the Centrosome into a Microtubule Nucleator. Biochemistry. 2018 ;57(1):30-37.
. The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC). Elife. 2022 ;11.
. Representative subsampling of sedimenting blood. Proc Math Phys Eng Sci. 2019 ;475(2227):20190223.
. Wind-Driven Formation of Ice Bridges in Straits. Phys Rev Lett. 2017 ;118(12):128701.
. A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating. mBio. 2020 ;11(2).
. Coexpressed subunits of dual genetic origin define a conserved supercomplex mediating essential protein import into chloroplasts. Proc Natl Acad Sci U S A. 2020 ;117(51):32739-32749.
. Phase separation vs aggregation behavior for model disordered proteins. J Chem Phys. 2021 ;155(12):125101.
. Concerted 2-5A-Mediated mRNA Decay and Transcription Reprogram Protein Synthesis in the dsRNA Response. Mol Cell. 2019 ;75(6):1218-1228.e6.
. A synthetic gene circuit for imaging-free detection of signaling pulses. Cell Syst. 2022 ;13(2):131-142.e13.
. Engineering combinatorial and dynamic decoders using synthetic immediate-early genes. Commun Biol. 2020 ;3(1):436.
. Long-range proton-coupled electron transfer in the class Ia ribonucleotide reductase. Essays Biochem. 2017 ;61(2):281-292.
. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands. Angew Chem Int Ed Engl. 2017 ;56(21):5738-5743.
. Bone metastasis and the metastatic niche. J Mol Med (Berl). 2015 ;93(11):1203-12.
. PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels. Science. 2015 ;349(6244):187-91.
. Genome Sequence of the Virulent Model Herpes Simplex Virus 1 Strain McKrae Demonstrates the Presence of at Least Two Widely Used Variant Strains. Microbiol Resour Announc. 2021 ;10(12).
. Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing. Nat Biotechnol. 2020 ;38(8):954-961.
. Implications of fibrotic extracellular matrix in diabetic retinopathy. Exp Biol Med (Maywood). 2022 ;247(13):1093-1102.
. Composition-dependent thermodynamics of intracellular phase separation. Nature. 2020 ;581(7807):209-214.
. Can phase separation buffer cellular noise?. Science. 2020 ;367(6476):364-365.
. Can phase separation buffer cellular noise?. Science. 2020 ;367(6476):364-365.
. Can phase separation buffer cellular noise?. Science. 2020 ;367(6476):364-365.
. Outer Membrane Protein Insertion by the β-barrel Assembly Machine. EcoSal Plus. 2019 ;8(2).
. Genomic analyses implicate noncoding de novo variants in congenital heart disease. Nat Genet. 2020 ;52(8):769-777.
. Ions in an AC Electric Field: Strong Long-Range Repulsion between Oppositely Charged Surfaces. Phys Rev Lett. 2020 ;125(5):056001.
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