Publications
] . Structural Basis of Neurohormone Perception by the Receptor Tyrosine Kinase Torso. Mol Cell. 2015 ;60(6):941-52.
. Structural Basis of Vesicle Formation at the Inner Nuclear Membrane. Cell. 2015 ;163(7):1692-701.
. Structural Biology of the Major Facilitator Superfamily Transporters. Annu Rev Biophys. 2015 ;44:257-83.
. Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3. Proc Natl Acad Sci U S A. 2015 ;112(13):3949-54.
. Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink. Nat Chem. 2015 ;7(5):431-437.
. Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution. Nature. 2015 ;517(7532):50-55.
. Structure of the voltage-gated calcium channel Cav1.1 complex. Science. 2015 ;350(6267):aad2395.
. Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition. Cell Res. 2015 ;25(4):401-11.
. A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors. Cell Rep. 2015 ;11(9):1486-500.
. A Systematic Ensemble Approach to Thermodynamic Modeling of Gene Expression from Sequence Data. Cell Syst. 2015 ;1(6):396-407.
. A systematic survey of the Cys2His2 zinc finger DNA-binding landscape. Nucleic Acids Res. 2015 ;43(3):1965-84.
. Searching for collective behavior in a large network of sensory neurons. PLoS Comput Biol. 2014 ;10(1):e1003408.
. Simple biochemical pathways far from steady state can provide switchlike and integrated responses. Biophys J. 2014 ;107(3):L1-L4.
. Simultaneous cellular-resolution optical perturbation and imaging of place cell firing fields. Nat Neurosci. 2014 ;17(12):1816-24.
. Social disadvantage, genetic sensitivity, and children's telomere length. Proc Natl Acad Sci U S A. 2014 ;111(16):5944-9.
. Solutions to the public goods dilemma in bacterial biofilms. Curr Biol. 2014 ;24(1):50-55.
. Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response. Science. 2014 ;343(6176):1244-8.
. Structure-activity relationships for a series of compounds that inhibit aggregation of the Alzheimer's peptide, Aβ42. Chem Biol Drug Des. 2014 ;84(5):505-12.
. subSeq: determining appropriate sequencing depth through efficient read subsampling. Bioinformatics. 2014 ;30(23):3424-6.
. A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics. Cell. 2014 ;158(6):1402-1414.
. Sec16 influences transitional ER sites by regulating rather than organizing COPII. Mol Biol Cell. 2013 ;24(21):3406-19.
. Structural advances for the major facilitator superfamily (MFS) transporters. Trends Biochem Sci. 2013 ;38(3):151-9.
. Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1. Proc Natl Acad Sci U S A. 2013 ;110(5):1652-7.
. Structural basis for the modular recognition of single-stranded RNA by PPR proteins. Nature. 2013 ;504(7478):168-71.
. Structural investigation of the proton-coupled secondary transporters. Curr Opin Struct Biol. 2013 ;23(4):483-91.