Publications
Individual and combined roles of the master regulators AphA and LuxR in control of the Vibrio harveyi quorum-sensing regulon. J Bacteriol. 2013 ;195(3):436-43.
. Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel. Nature. 2009 ;462(7272):467-72.
. Telomere les(i/s)ons from a telomerase RNA mutant. Cell Cycle. 2015 ;14(24):3769-70.
. Telomerase RNA stem terminus element affects template boundary element function, telomere sequence, and shelterin binding. Proc Natl Acad Sci U S A. 2015 ;112(36):11312-7.
. The Heidelberg Screen for Pattern Mutants of Drosophila: A Personal Account. Annu Rev Cell Dev Biol. 2016 ;32:1-46.
. Decoding disease: from genomes to networks to phenotypes. Nat Rev Genet. 2021 ;22(12):774-790.
. The mechanism of Na⁺/K⁺ selectivity in mammalian voltage-gated sodium channels based on molecular dynamics simulation. Biophys J. 2013 ;104(11):2401-9.
. A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols. Science. 2021 ;371(6533).
. Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion. Nat Commun. 2017 ;8(1):327.
. Inference of Multisite Phosphorylation Rate Constants and Their Modulation by Pathogenic Mutations. Curr Biol. 2020 ;30(5):877-882.e6.
. Chaperoning SNARE Folding and Assembly. Annu Rev Biochem. 2021 ;90:581-603.
. CanE, an Iron/2-Oxoglutarate-Dependent Lasso Peptide Hydroxylase from . ACS Chem Biol. 2020 ;15(4):890-894.
. Deep learning sequence-based ab initio prediction of variant effects on expression and disease risk. Nat Genet. 2018 ;50(8):1171-1179.
. Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk. Nat Genet. 2019 ;51(6):973-980.
. Predicting effects of noncoding variants with deep learning-based sequence model. Nat Methods. 2015 ;12(10):931-4.
. Mitochondria and Cancer. Mol Cell. 2016 ;61(5):667-676.
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