Publications
Modeling transcriptional regulation of model species with deep learning. Genome Res. 2021 ;31(6):1097-1105.
. Molecular mechanisms underlying cellular effects of human MEK1 mutations. Mol Biol Cell. 2021 ;32(9):974-983.
. Motif-pattern dependence of biomolecular phase separation driven by specific interactions. PLoS Comput Biol. 2021 ;17(12):e1009748.
. mTORC1 promotes cell growth via mA-dependent mRNA degradation. Mol Cell. 2021 ;81(10):2064-2075.e8.
. A multilayered scaffold for regeneration of smooth muscle and connective tissue layers. J Biomed Mater Res A. 2021 ;109(5):733-744.
. NAD flux is maintained in aged mice despite lower tissue concentrations. Cell Syst. 2021 ;12(12):1160-1172.e4.
. NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma. Cell Rep. 2021 ;35(11):109238.
. A neural mA/Ythdf pathway is required for learning and memory in Drosophila. Nat Commun. 2021 ;12(1):1458.
. New mouse models for high resolution and live imaging of planar cell polarity proteins in vivo. Development. 2021 ;148(18).
. The nucleolus as a multiphase liquid condensate. Nat Rev Mol Cell Biol. 2021 ;22(3):165-182.
. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nat Chem Biol. 2021 ;17(4):403-411.
. Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents. Proc Natl Acad Sci U S A. 2021 ;118(3).
. Overriding native cell coordination enhances external programming of collective cell migration. Proc Natl Acad Sci U S A. 2021 ;118(29).
. Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch. Cell Rep. 2021 ;35(12):109280.
. Presenilin 1 phosphorylation regulates amyloid-β degradation by microglia. Mol Psychiatry. 2021 ;26(10):5620-5635.
. Properties of repression condensates in living Ciona embryos. Nat Commun. 2021 ;12(1):1561.
. Protocol for transgenerational learned pathogen avoidance behavior assays in . STAR Protoc. 2021 ;2(1):100384.
. Quantitative flux analysis in mammals. Nat Metab. 2021 ;3(7):896-908.
. Quorum Sensing in Streptococcus mutans Regulates Production of Tryglysin, a Novel RaS-RiPP Antimicrobial Compound. mBio. 2021 ;12(2).
. Rapid Macrosatellite Evolution Promotes X-Linked Hybrid Male Sterility in a Feline Interspecies Cross. Mol Biol Evol. 2021 ;38(12):5588-5609.
. Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop. J Cell Biol. 2021 ;220(5).
. Redundant enhancers in the iab-5 domain cooperatively activate Abd-B in the A5 and A6 abdominal segments of Drosophila. Development. 2021 ;148(19).
. Restoring metabolism of myeloid cells reverses cognitive decline in ageing. Nature. 2021 ;590(7844):122-128.
. Rifamycin antibiotics and the mechanisms of their failure. J Antibiot (Tokyo). 2021 ;74(11):786-798.
. The role of the Cer1 transposon in horizontal transfer of transgenerational memory. Cell. 2021 ;184(18):4697-4712.e18.
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