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2021
Cofer EM, Raimundo J, Tadych A, Yamazaki Y, Wong AK, Theesfeld CL, et al. Modeling transcriptional regulation of model species with deep learning. Genome Res. 2021 ;31(6):1097-1105.
Marmion RA, Yang L, Goyal Y, Jindal GA, Wetzel JL, Singh M, et al. Molecular mechanisms underlying cellular effects of human MEK1 mutations. Mol Biol Cell. 2021 ;32(9):974-983.
Weiner BG, Pyo AGT, Meir Y, Wingreen NS. Motif-pattern dependence of biomolecular phase separation driven by specific interactions. PLoS Comput Biol. 2021 ;17(12):e1009748.
Cho S, Lee G, Pickering BF, Jang C, Park JH, He L, et al. mTORC1 promotes cell growth via mA-dependent mRNA degradation. Mol Cell. 2021 ;81(10):2064-2075.e8.
Garrison CM, Singh-Varma A, Pastino AK, Steele JAM, Kohn J, N Murthy S, et al. A multilayered scaffold for regeneration of smooth muscle and connective tissue layers. J Biomed Mater Res A. 2021 ;109(5):733-744.
McReynolds MR, Chellappa K, Chiles E, Jankowski C, Shen Y, Chen L, et al. NAD flux is maintained in aged mice despite lower tissue concentrations. Cell Syst. 2021 ;12(12):1160-1172.e4.
Schild T, McReynolds MR, Shea C, Low V, Schaffer BE, Asara JM, et al. NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma. Cell Rep. 2021 ;35(11):109238.
Kan L, Ott S, Joseph B, Park ESil, Dai W, Kleiner RE, et al. A neural mA/Ythdf pathway is required for learning and memory in Drosophila. Nat Commun. 2021 ;12(1):1458.
Basta LP, Hill-Oliva M, Paramore SV, Sharan R, Goh A, Biswas A, et al. New mouse models for high resolution and live imaging of planar cell polarity proteins in vivo. Development. 2021 ;148(18).
Lafontaine DLJ, Riback JA, Bascetin R, Brangwynne CP. The nucleolus as a multiphase liquid condensate. Nat Rev Mol Cell Biol. 2021 ;22(3):165-182.
Bagert JD, Mitchener MM, Patriotis AL, Dul BE, Wojcik F, Nacev BA, et al. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nat Chem Biol. 2021 ;17(4):403-411.
Huang J, Yuan Y, Zhao N, Pu D, Tang Q, Zhang S, et al. Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents. Proc Natl Acad Sci U S A. 2021 ;118(3).
Shim G, Devenport D, Cohen DJ. Overriding native cell coordination enhances external programming of collective cell migration. Proc Natl Acad Sci U S A. 2021 ;118(29).
Dine E, Reed EH, Toettcher JE. Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch. Cell Rep. 2021 ;35(12):109280.
Ledo JHenrique, Liebmann T, Zhang R, Chang JC, Azevedo EP, Wong E, et al. Presenilin 1 phosphorylation regulates amyloid-β degradation by microglia. Mol Psychiatry. 2021 ;26(10):5620-5635.
Treen N, Shimobayashi SF, Eeftens J, Brangwynne CP, Levine M. Properties of repression condensates in living Ciona embryos. Nat Commun. 2021 ;12(1):1561.
Moore RS, Kaletsky R, Murphy CT. Protocol for transgenerational learned pathogen avoidance behavior assays in . STAR Protoc. 2021 ;2(1):100384.
Bartman CR, TeSlaa T, Rabinowitz JD. Quantitative flux analysis in mammals. Nat Metab. 2021 ;3(7):896-908.
Rued BE, Covington BC, Bushin LB, Szewczyk G, Laczkovich I, Seyedsayamdost MR, et al. Quorum Sensing in Streptococcus mutans Regulates Production of Tryglysin, a Novel RaS-RiPP Antimicrobial Compound. mBio. 2021 ;12(2).
Bredemeyer KR, Seabury CM, Stickney MJ, McCarrey JR, vonHoldt BM, Murphy WJ. Rapid Macrosatellite Evolution Promotes X-Linked Hybrid Male Sterility in a Feline Interspecies Cross. Mol Biol Evol. 2021 ;38(12):5588-5609.
Lee Y, Jung Y, Jeong D-E, Hwang W, Ham S, Park H-EH, et al. Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop. J Cell Biol. 2021 ;220(5).
Postika N, Schedl P, Georgiev P, Kyrchanova O. Redundant enhancers in the iab-5 domain cooperatively activate Abd-B in the A5 and A6 abdominal segments of Drosophila. Development. 2021 ;148(19).
Minhas PS, Latif-Hernandez A, McReynolds MR, Durairaj AS, Wang Q, Rubin A, et al. Restoring metabolism of myeloid cells reverses cognitive decline in ageing. Nature. 2021 ;590(7844):122-128.
Adams RA, Leon G, Miller NM, Reyes SP, Thantrong CH, Thokkadam AM, et al. Rifamycin antibiotics and the mechanisms of their failure. J Antibiot (Tokyo). 2021 ;74(11):786-798.
Moore RS, Kaletsky R, Lesnik C, Cota V, Blackman E, Parsons LR, et al. The role of the Cer1 transposon in horizontal transfer of transgenerational memory. Cell. 2021 ;184(18):4697-4712.e18.