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2021
Li VR, Zhang Z, Troyanskaya OG. CROTON: an automated and variant-aware deep learning framework for predicting CRISPR/Cas9 editing outcomes. Bioinformatics. 2021 ;37(Suppl_1):i342-i348.
Wong AK, Sealfon RSG, Theesfeld CL, Troyanskaya OG. Decoding disease: from genomes to networks to phenotypes. Nat Rev Genet. 2021 ;22(12):774-790.
Wong AK, Sealfon RSG, Theesfeld CL, Troyanskaya OG. Decoding disease: from genomes to networks to phenotypes. Nat Rev Genet. 2021 ;22(12):774-790.
Zhao Z, Tian D, McBride CS. Development of a pan-neuronal genetic driver in mosquitoes. Cell Rep Methods. 2021 ;1(3).
Kumar S, Nandi A, Singh S, Regulapati R, Li N, Tobias JW, et al. Dll1 quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway. Nat Commun. 2021 ;12(1):432.
Wu A, Zhi J, Tian T, Cihan A, Cevher MA, Liu Z, et al. DOT1L complex regulates transcriptional initiation in human erythroleukemic cells. Proc Natl Acad Sci U S A. 2021 ;118(27).
Etzion-Fuchs A, Todd DA, Singh M. dSPRINT: predicting DNA, RNA, ion, peptide and small molecule interaction sites within protein domains. Nucleic Acids Res. 2021 ;49(13):e78.
Lovelett RJ, Zhao EM, Lalwani MA, Toettcher JE, Kevrekidis IG, Avalos JL. Dynamical Modeling of Optogenetic Circuits in Yeast for Metabolic Engineering Applications. ACS Synth Biol. 2021 ;10(2):219-227.
Hart KC, Sim JYong, Hopcroft MA, Cohen DJ, Tan J, W Nelson J, et al. An Easy-to-Fabricate Cell Stretcher Reveals Density-Dependent Mechanical Regulation of Collective Cell Movements in Epithelia. Cell Mol Bioeng. 2021 ;14(6):569-581.
Posfai E, Schell JPaul, Janiszewski A, Rovic I, Murray A, Bradshaw B, et al. Evaluating totipotency using criteria of increasing stringency. Nat Cell Biol. 2021 ;23(1):49-60.
Posfai E, Schell JPaul, Janiszewski A, Rovic I, Murray A, Bradshaw B, et al. Evaluating totipotency using criteria of increasing stringency. Nat Cell Biol. 2021 ;23(1):49-60.
Arita Y, Kim G, Li Z, Friesen H, Turco G, Wang RY, et al. A genome-scale yeast library with inducible expression of individual genes. Mol Syst Biol. 2021 ;17(6):e10207.
Park CY, Zhou J, Wong AK, Chen KM, Theesfeld CL, Darnell RB, et al. Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk. Nat Genet. 2021 ;53(2):166-173.
Park CY, Zhou J, Wong AK, Chen KM, Theesfeld CL, Darnell RB, et al. Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk. Nat Genet. 2021 ;53(2):166-173.
Zhao S, Chuh KN, Zhang B, Dul BE, Thompson RE, Farrelly LA, et al. Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout. Proc Natl Acad Sci U S A. 2021 ;118(6).
Strom AR, Biggs RJ, Banigan EJ, Wang X, Chiu K, Herman C, et al. HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics. Elife. 2021 ;10.
Strom AR, Biggs RJ, Banigan EJ, Wang X, Chiu K, Herman C, et al. HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics. Elife. 2021 ;10.
Pearson VR, Bosse JB, Koyuncu OO, Scherer J, Toruno C, Robinson R, et al. Identification of African Elephant Polyomavirus in wild elephants and the creation of a vector expressing its viral tumor antigens to transform elephant primary cells. PLoS One. 2021 ;16(2):e0244334.
Phan T, Nguyen VH, Buettner R, Morales C, Yang L, Wong P, et al. Inhibition of pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer. Int J Biol Sci. 2021 ;17(9):2240-2251.
Taylor IR, Paczkowski JE, Jeffrey PD, Henke BR, Smith CD, Bassler BL. Inhibitor Mimetic Mutations in the PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production. ACS Chem Biol. 2021 ;16(4):740-752.
Tien J, Dance YW, Ghani U, Seibel AJ, Nelson CM. Interstitial Hypertension Suppresses Escape of Human Breast Tumor Cells Convection of Interstitial Fluid. Cell Mol Bioeng. 2021 ;14(2):147-159.
Johnston RA, Rheinwald JG, vonHoldt BM, Stahler DR, Lowry W, Tung J, et al. K Locus Effects in Gray Wolves: Experimental Assessment of TLR3 Signaling and the Gene Expression Response to Canine Distemper Virus. J Hered. 2021 ;112(5):458-468.
Tkačik G, Gregor T. The many bits of positional information. Development. 2021 ;148(2).
Rabie EM, Zhang SX, Kourouklis AP, A Kilinc N, Simi AK, Radisky DC, et al. Matrix degradation and cell proliferation are coupled to promote invasion and escape from an engineered human breast microtumor. Integr Biol (Camb). 2021 ;13(1):17-29.
Cable J, Pourquié O, Wellen KE, Finley LWS, Aulehla A, Gould AP, et al.. Metabolic decisions in development and disease-a Keystone Symposia report. Ann N Y Acad Sci. 2021 ;1506(1):55-73.