Publications
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A Glimpse of Membrane Transport through Structures-Advances in the Structural Biology of the GLUT Glucose Transporters. J Mol Biol. 2017 ;429(17):2710-2725.
. Structure of the Na1.4-β1 Complex from Electric Eel. Cell. 2017 ;170(3):470-482.e11.
. Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution. Nature. 2015 ;517(7532):50-55.
. Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB. Proc Natl Acad Sci U S A. 2018 ;115(51):E12053-E12062.
. Structural Biology of the Major Facilitator Superfamily Transporters. Annu Rev Biophys. 2015 ;44:257-83.
. Environmental fluctuation governs selection for plasticity in biofilm production. ISME J. 2017 ;11(7):1569-1577.
. Structural investigation of the proton-coupled secondary transporters. Curr Opin Struct Biol. 2013 ;23(4):483-91.
. Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion. Nat Commun. 2017 ;8(1):327.
. Structural advances for the major facilitator superfamily (MFS) transporters. Trends Biochem Sci. 2013 ;38(3):151-9.
. Laboratory layered latte. Nat Commun. 2017 ;8(1):1960.
. Self-Similar Draining near a Vertical Edge. Phys Rev Lett. 2020 ;125(6):064502.
. Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells. Science. 2020 ;369(6502):397-403.
. A genetics-free method for high-throughput discovery of cryptic microbial metabolites. Nat Chem Biol. 2019 ;15(2):161-168.
. Genetic analysis of the cooperative tumorigenic effects of targeted deletions of tumor suppressors , , , and in neuroendocrine tumors in mice. Oncotarget. 2020 ;11(28):2718-2739.
. Discovery and Functional Characterization of a Yeast Sugar Alcohol Phosphatase. ACS Chem Biol. 2018 ;13(10):3011-3020.
. Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens. J Am Chem Soc. 2017 ;139(27):9203-9212.
. Structural mechanism of demethylation and inactivation of protein phosphatase 2A. Cell. 2008 ;133(1):154-63.
. Molecular mechanism for inhibition of a critical component in the Arabidopsis thaliana abscisic acid signal transduction pathways, SnRK2.6, by protein phosphatase ABI1. J Biol Chem. 2012 ;287(1):794-802.
. Discovery of quorum quenchers targeting the membrane-embedded sensor domain of the receptor histidine kinase, AgrC. Chem Commun (Camb). 2020 ;56(76):11223-11226.
. Identification of a Molecular Latch that Regulates Staphylococcal Virulence. Cell Chem Biol. 2019 ;26(4):548-558.e4.
. The mechanism of Na⁺/K⁺ selectivity in mammalian voltage-gated sodium channels based on molecular dynamics simulation. Biophys J. 2013 ;104(11):2401-9.
. Regulation of uptake and processing of the quorum-sensing autoinducer AI-2 in Escherichia coli. J Bacteriol. 2005 ;187(1):238-48.
. LuxS quorum sensing: more than just a numbers game. Curr Opin Microbiol. 2003 ;6(2):191-7.
. Interference with AI-2-mediated bacterial cell-cell communication. Nature. 2005 ;437(7059):750-3.
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