Publications
Novel Pyrrolo[3,2-]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy. Mol Cancer Ther. 2019 ;18(10):1787-1799.
. Impact of the adenoviral E4 Orf3 protein on the activity and posttranslational modification of p53. J Virol. 2015 ;89(6):3209-20.
. Extensive post-translational modification of active and inactivated forms of endogenous p53. Mol Cell Proteomics. 2014 ;13(1):1-17.
. Quantum Calculations Indicate Effective Electron Transfer between FMN and Benzoquinone in a New Crystal Structure of Escherichia coli WrbA. J Phys Chem B. 2016 ;120(22):4867-77.
. orco mutant mosquitoes lose strong preference for humans and are not repelled by volatile DEET. Nature. 2013 ;498(7455):487-91.
. Toward an integrative molecular approach to wildlife disease. Conserv Biol. 2018 ;32(4):798-807.
. Urban colonization through multiple genetic lenses: The city-fox phenomenon revisited. Ecol Evol. 2019 ;9(4):2046-2060.
. Of microbes and mange: consistent changes in the skin microbiome of three canid species infected with Sarcoptes scabiei mites. Parasit Vectors. 2019 ;12(1):488.
. Ear mite infection is associated with altered microbial communities in genetically depauperate Santa Catalina Island foxes (Urocyon littoralis catalinae). Mol Ecol. 2020 ;29(8):1463-1475.
. Ubiquitin utilizes an acidic surface patch to alter chromatin structure. Nat Chem Biol. 2017 ;13(1):105-110.
. A molecular engineering toolbox for the structural biologist. Q Rev Biophys. 2017 ;50:e7.
. North Andean origin and diversification of the largest ithomiine butterfly genus. Sci Rep. 2017 ;7:45966.
. Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc Natl Acad Sci U S A. 2017 ;114(39):10420-10425.
. . Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors. Nat Med. 2017 ;23(2):235-241.
. Emerging Chemistry Strategies for Engineering Native Chromatin. J Am Chem Soc. 2017 ;139(27):9090-9096.
. A basic motif anchoring ISWI to nucleosome acidic patch regulates nucleosome spacing. Nat Chem Biol. 2020 ;16(2):134-142.
. Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity. Oncotarget. 2017 ;8(34):57121-57133.
. Discriminatory Power of Combinatorial Antigen Recognition in Cancer T Cell Therapies. Cell Syst. 2020 ;11(3):215-228.e5.
. Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity. Oncotarget. 2017 ;.
. ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference. Nature. 2017 ;548(7669):607-611.
. Structure of a fucose transporter in an outward-open conformation. Nature. 2010 ;467(7316):734-8.
. High-fidelity coding with correlated neurons. PLoS Comput Biol. 2014 ;10(11):e1003970.
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