Publications
A Scalable Platform for Functional Nanomaterials via Bubble-Bursting. Adv Mater. 2016 ;28(21):4047-52.
. Soft viscoelastic properties of nuclear actin age oocytes due to gravitational creep. Sci Rep. 2015 ;5:16607.
. SIG1459: A novel phytyl-cysteine derived TLR2 modulator with in vitro and clinical anti-acne activity. Exp Dermatol. 2018 ;27(9):993-999.
. Structure and Function of the Influenza Virus Transcription and Replication Machinery. Cold Spring Harb Perspect Med. 2020 ;10(9).
. Structure of human Ca2.2 channel blocked by the painkiller ziconotide. Nature. 2021 ;596(7870):143-147.
. Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Ca 1.1 by Dihydropyridine Compounds*. Angew Chem Int Ed Engl. 2021 ;60(6):3131-3137.
. Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP. Nat Commun. 2020 ;11(1):2173.
. SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia. Leukemia. 2021 ;35(2):377-388.
. Silver-Based Self-Powered pH-Sensitive Pump and Sensor. Langmuir. 2020 ;36(27):7948-7955.
. The signature motif of the Saccharomyces cerevisiae Pif1 DNA helicase is essential in vivo for mitochondrial and nuclear functions and in vitro for ATPase activity. Nucleic Acids Res. 2018 ;46(16):8357-8370.
. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Nat Chem Biol. 2020 ;16(7):731-739.
. Small Biomolecules for Big Applications. ACS Cent Sci. 2018 ;4(4):437-439.
. Structural Basis for the Modulation of Ryanodine Receptors. Trends Biochem Sci. 2021 ;46(6):489-501.
. Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition. Cell Res. 2015 ;25(4):401-11.
. Structural basis for the recognition of Sonic Hedgehog by human Patched1. Science. 2018 ;361(6402).
. Smooth muscle differentiation shapes domain branches during mouse lung development. Development. 2019 ;146(22).
. Scaling probabilistic models of genetic variation to millions of humans. Nat Genet. 2016 ;48(12):1587-1590.
. Starved Escherichia coli preserve reducing power under nitric oxide stress. Biochem Biophys Res Commun. 2016 ;476(1):29-34.
. Single-Particle Dynamic Light Scattering: Shapes of Individual Nanoparticles. Nano Lett. 2019 ;19(8):5530-5536.
. Systems-level analysis of mechanisms regulating yeast metabolic flux. Science. 2016 ;354(6311).
. Structural Basis of Vesicle Formation at the Inner Nuclear Membrane. Cell. 2015 ;163(7):1692-701.
. Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response. Science. 2014 ;343(6176):1244-8.
. Substratum stiffness tunes proliferation downstream of Wnt3a in part by regulating integrin-linked kinase and frizzled-1. J Cell Sci. 2018 ;131(8).
. Synthesis of ADP-Ribosylated Histones Reveals Site-Specific Impacts on Chromatin Structure and Function. J Am Chem Soc. 2021 ;143(29):10847-10852.
. .