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Shirvani-Dastgerdi E, Winer BY, Celià-Terrassa T, Kang Y, Tabernero D, Yagmur E, et al.. Selection of the highly replicative and partially multidrug resistant rtS78T HBV polymerase mutation during TDF-ETV combination therapy. J Hepatol. 2017 ;67(2):246-254.
Huang W, Liu M, S Yan F, Yan N. Structure-based assessment of disease-related mutations in human voltage-gated sodium channels. Protein Cell. 2017 ;8(6):401-438.
Rajeshkumar NV, Yabuuchi S, Pai SG, De Oliveira E, Kamphorst JJ, Rabinowitz JD, et al. Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin. Clin Cancer Res. 2017 ;23(18):5639-5647.
Kyrchanova O, Kurbidaeva A, Sabirov M, Postika N, Wolle D, Aoki T, et al. The bithorax complex iab-7 Polycomb response element has a novel role in the functioning of the Fab-7 chromatin boundary. PLoS Genet. 2018 ;14(8):e1007442.
Postika N, Metzler M, Affolter M, Müller M, Schedl P, Georgiev P, et al.. Boundaries mediate long-distance interactions between enhancers and promoters in the Drosophila Bithorax complex. PLoS Genet. 2018 ;14(12):e1007702.
Gibney PA, Schieler A, Chen JC, Bacha-Hummel JM, Botstein M, Volpe M, et al. Common and divergent features of galactose-1-phosphate and fructose-1-phosphate toxicity in yeast. Mol Biol Cell. 2018 ;29(8):897-910.
Donnelly AE, Murphy GS, Digianantonio KM, Hecht MH. A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli. Nat Chem Biol. 2018 ;14(3):253-255.
Zhou J, Theesfeld CL, Yao K, Chen KM, Wong AK, Troyanskaya OG. Deep learning sequence-based ab initio prediction of variant effects on expression and disease risk. Nat Genet. 2018 ;50(8):1171-1179.
Jenness C, Giunta S, Müller MM, Kimura H, Muir TW, Funabiki H. HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome. Proc Natl Acad Sci U S A. 2018 ;115(5):E876-E885.
Ali MZulfikar, Wingreen NS, Mukhopadhyay R. Hidden long evolutionary memory in a model biochemical network. Phys Rev E. 2018 ;97(4-1):040401.
Shi H, Bratton BP, Gitai Z, Huang KCasey. How to Build a Bacterial Cell: MreB as the Foreman of E. coli Construction. Cell. 2018 ;172(6):1294-1305.
Cadoff EB, Sheffer R, Wientroub S, Ovadia D, Meiner V, Schwarzbauer JE. Mechanistic insights into the cellular effects of a novel FN1 variant associated with a spondylometaphyseal dysplasia. Clin Genet. 2018 ;94(5):429-437.
Jiao J, He M, Port SA, Baker RW, Xu Y, Qu H, et al. Munc18-1 catalyzes neuronal SNARE assembly by templating SNARE association. Elife. 2018 ;7.
Pan X, Li Z, Zhou Q, Shen H, Wu K, Huang X, et al. Structure of the human voltage-gated sodium channel Na1.4 in complex with β1. Science. 2018 ;362(6412).
Paczkowski JE, McCready AR, Cong J-P, Li Z, Jeffrey PD, Smith CD, et al. An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. ACS Chem Biol. 2019 ;14(3):378-389.
Ueberschär M, Wang H, Zhang C, Kondo S, Aoki T, Schedl P, et al.. BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila. Nat Commun. 2019 ;10(1):5700.
Lum KK, Howard TR, Pan C, Cristea IM. Charge-Mediated Pyrin Oligomerization Nucleates Antiviral IFI16 Sensing of Herpesvirus DNA. mBio. 2019 ;10(4).
Aedo SJ, Ma HR, Brynildsen MP. Checks and Balances with Use of the Keio Collection for Phenotype Testing. Methods Mol Biol. 2019 ;1927:125-138.
Barr J, Gilmutdinov R, Wang L, Shidlovskii, ii Y, Schedl P. The CPEB Protein Orb Specifies Oocyte Fate by a 3'UTR-Dependent Autoregulatory Loop. Genetics. 2019 ;213(4):1431-1446.
Barr J, Charania S, Gilmutdinov R, Yakovlev K, Shidlovskii, ii Y, Schedl P. The CPEB translational regulator, Orb, functions together with Par proteins to polarize the Drosophila oocyte. PLoS Genet. 2019 ;15(3):e1008012.
Box K, Joyce BW, Devenport D. Epithelial geometry regulates spindle orientation and progenitor fate during formation of the mammalian epidermis. Elife. 2019 ;8.
Nacev BA, Feng L, Bagert JD, Lemiesz AE, Gao JJ, Soshnev AA, et al. The expanding landscape of 'oncohistone' mutations in human cancers. Nature. 2019 ;567(7749):473-478.
Hart EM, O'Connell A, Tang K, Wzorek JS, Grabowicz M, Kahne D, et al. Fine-Tuning of σ Activation Suppresses Multiple Assembly-Defective Mutations in Escherichia coli. J Bacteriol. 2019 ;201(11).
Taylor CA, Cormier KW, Keenan SE, Earnest S, Stippec S, Wichaidit C, et al. Functional divergence caused by mutations in an energetic hotspot in ERK2. Proc Natl Acad Sci U S A. 2019 ;116(31):15514-15523.
Li X, Patena W, Fauser F, Jinkerson RE, Saroussi S, Meyer MT, et al. A genome-wide algal mutant library and functional screen identifies genes required for eukaryotic photosynthesis. Nat Genet. 2019 ;51(4):627-635.