Publications
A genome-wide algal mutant library and functional screen identifies genes required for eukaryotic photosynthesis. Nat Genet. 2019 ;51(4):627-635.
. Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin. Proc Natl Acad Sci U S A. 2020 ;117(48):30465-30475.
. The bithorax complex iab-7 Polycomb response element has a novel role in the functioning of the Fab-7 chromatin boundary. PLoS Genet. 2018 ;14(8):e1007442.
. Architectural protein Pita cooperates with dCTCF in organization of functional boundaries in Bithorax complex. Development. 2017 ;144(14):2663-2672.
. A Suppressor Mutation That Creates a Faster and More Robust σE Envelope Stress Response. J Bacteriol. 2016 ;198(17):2345-51.
. Systematic domain-based aggregation of protein structures highlights DNA-, RNA- and other ligand-binding positions. Nucleic Acids Res. 2019 ;47(2):582-593.
. Stable Pseudohyphal Growth in Budding Yeast Induced by Synergism between Septin Defects and Altered MAP-kinase Signaling. PLoS Genet. 2015 ;11(12):e1005684.
. Formation of a TBX20-CASZ1 protein complex is protective against dilated cardiomyopathy and critical for cardiac homeostasis. PLoS Genet. 2017 ;13(9):e1007011.
. Mechanisms and causality in molecular diseases. Hist Philos Life Sci. 2017 ;39(4):35.
. Drosophila Dosage Compensation Loci Associate with a Boundary-Forming Insulator Complex. Mol Cell Biol. 2017 ;37(21).
. C. elegans interprets bacterial non-coding RNAs to learn pathogenic avoidance. Nature. 2020 ;586(7829):445-451.
. The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators. Nature. 2016 ;529(7584):92-6.
. Transcriptional Profiling of C. elegans Adult Cells and Tissues with Age. Methods Mol Biol. 2020 ;2144:177-186.
. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science. 2009 ;323(5922):1693-7.
. RASopathies: unraveling mechanisms with animal models. Dis Model Mech. 2015 ;8(8):769-82.
. In vivo severity ranking of Ras pathway mutations associated with developmental disorders. Proc Natl Acad Sci U S A. 2017 ;114(3):510-515.
. . Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation. Proc Natl Acad Sci U S A. 2016 ;113(44):12420-12425.
. HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome. Proc Natl Acad Sci U S A. 2018 ;115(5):E876-E885.
. Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase. Proc Natl Acad Sci U S A. 2019 ;116(17):8295-8300.
. c21orf59/kurly Controls Both Cilia Motility and Polarization. Cell Rep. 2016 ;14(8):1841-9.
. A Rubisco-binding protein is required for normal pyrenoid number and starch sheath morphology in . Proc Natl Acad Sci U S A. 2019 ;116(37):18445-18454.
. Structure-based assessment of disease-related mutations in human voltage-gated sodium channels. Protein Cell. 2017 ;8(6):401-438.
. Network-Based Coverage of Mutational Profiles Reveals Cancer Genes. Cell Syst. 2017 ;5(3):221-229.e4.
. Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin. Proc Natl Acad Sci U S A. 2015 ;112(33):10365-70.
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