Publications
In Vitro Reconstitution of OxyC Activity Enables Total Chemoenzymatic Syntheses of Vancomycin Aglycone Variants. Angew Chem Int Ed Engl. 2018 ;57(27):8048-8052.
. In Vitro Reconstitution of OxyA Enzymatic Activity Clarifies Late Steps in Vancomycin Biosynthesis. ACS Chem Biol. 2017 ;12(9):2248-2253.
. Mapping and Exploiting the Promiscuity of OxyB toward the Biocatalytic Production of Vancomycin Aglycone Variants. ACS Catal. 2020 ;10(16):9287-9298.
. Increasing the uptake of carbon dioxide. Elife. 2020 ;9.
. Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle. Cell Metab. 2016 ;24(2):269-82.
. Mexican Wolves Are a Valid Subspecies and an Appropriate Conservation Target. J Hered. 2015 ;106(4):415-6.
. A genetic analysis of the functions of LuxN: a two-component hybrid sensor kinase that regulates quorum sensing in Vibrio harveyi. Mol Microbiol. 2000 ;35(1):139-49.
. Programmable Inhibition and Detection of RNA Viruses Using Cas13. Mol Cell. 2019 ;76(5):826-837.e11.
. Transient RNA structures cause aberrant influenza virus replication and innate immune activation. Sci Adv. 2022 ;8(36):eabp8655.
. Cryptic protein-protein interaction motifs in the cytoplasmic domain of MHCI proteins. BMC Immunol. 2016 ;17(1):24.
. Post-transcriptional gene regulation by an Hfq-independent small RNA in Caulobacter crescentus. Nucleic Acids Res. 2018 ;46(20):10969-10982.
. Access to site-specific Fc-cRGD peptide conjugates through streamlined expressed protein ligation. Org Biomol Chem. 2016 ;14(40):9549-9553.
. Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans. PLoS Genet. 2016 ;12(2):e1005889.
. Enhancer Control of Transcriptional Bursting. Cell. 2016 ;166(2):358-368.
. Mapping the binding interface of ERK and transcriptional repressor Capicua using photocrosslinking. Proc Natl Acad Sci U S A. 2015 ;112(28):8590-5.
. Confinement size determines the architecture of Ran-induced microtubule networks. Soft Matter. 2021 ;17(24):5921-5931.
. Structure of human Ca2.2 channel blocked by the painkiller ziconotide. Nature. 2021 ;596(7870):143-147.
. Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Ca 1.1 by Dihydropyridine Compounds*. Angew Chem Int Ed Engl. 2021 ;60(6):3131-3137.
. An oscillatory circuit underlying the detection of disruptions in temporally-periodic patterns. Network. 2009 ;20(2):106-35.
. Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na channels in nanodisc. Proc Natl Acad Sci U S A. 2020 ;117(25):14187-14193.
. Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP. Nat Commun. 2020 ;11(1):2173.
. Live Imaging of mRNA Synthesis in Drosophila. Methods Mol Biol. 2018 ;1649:349-357.
. A new role for proteins subunits of RNase P: stabilization of the telomerase holoenzyme. Microb Cell. 2020 ;7(9):250-254.
. The Tumor Metabolic Microenvironment: Lessons from Lactate. Cancer Res. 2019 ;79(13):3155-3162.
. SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia. Leukemia. 2021 ;35(2):377-388.
.