Publications
Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors. Nat Med. 2017 ;23(2):235-241.
. Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production. Cell Metab. 2016 ;23(6):1154-1166.
. A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly. Science. 2015 ;349(6252):1111-4.
. Directional reversals enable Myxococcus xanthus cells to produce collective one-dimensional streams during fruiting-body formation. J R Soc Interface. 2015 ;12(109):20150049.
. Discovery and Biosynthesis of Streptosactin, a Sactipeptide with an Alternative Topology Encoded by Commensal Bacteria in the Human Microbiome. J Am Chem Soc. 2020 ;142(38):16265-16275.
. Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine. Cell Host Microbe. 2014 ;16(4):495-503.
. Discovery and dissection of metabolic oscillations in the microaerobic nitric oxide response network of Escherichia coli. Proc Natl Acad Sci U S A. 2016 ;113(12):E1757-66.
. Discovery and Functional Characterization of a Yeast Sugar Alcohol Phosphatase. ACS Chem Biol. 2018 ;13(10):3011-3020.
. Discovery and structure of the antimicrobial lasso peptide citrocin. J Biol Chem. 2019 ;294(17):6822-6830.
. Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens. J Am Chem Soc. 2017 ;139(27):9203-9212.
. Discovery of a Cryptic Depsipeptide from Streptomyces ghanaensis via MALDI-MS-Guided High-Throughput Elicitor Screening. Angew Chem Int Ed Engl. 2020 ;59(51):23005-23009.
. Discovery of a New Class I Ribonucleotide Reductase with an Essential DOPA Radical and NO Metal as an Initiator of Long-Range Radical Transfer. Biochemistry. 2019 ;58(6):435-437.
. Discovery of a New Song Mode in Drosophila Reveals Hidden Structure in the Sensory and Neural Drivers of Behavior. Curr Biol. 2018 ;28(15):2400-2412.e6.
. Discovery of as a global regulator of secondary metabolism and virulence in E264. Proc Natl Acad Sci U S A. 2017 ;114(14):E2920-E2928.
. Discovery of PqsE Thioesterase Inhibitors for Using DNA-Encoded Small Molecule Library Screening. ACS Chem Biol. 2020 ;15(2):446-456.
. Discovery of quorum quenchers targeting the membrane-embedded sensor domain of the receptor histidine kinase, AgrC. Chem Commun (Camb). 2020 ;56(76):11223-11226.
. Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases. Cell. 2017 ;168(3):517-526.e18.
. Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex. Chembiochem. 2020 ;21(9):1335-1340.
. Discriminatory Power of Combinatorial Antigen Recognition in Cancer T Cell Therapies. Cell Syst. 2020 ;11(3):215-228.e5.
. Disease outbreaks select for mate choice and coat color in wolves. Science. 2022 ;378(6617):300-303.
. Disruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway. Proc Natl Acad Sci U S A. 2016 ;113(11):E1565-74.
. Dissecting Protein Complexes in Branching Microtubule Nucleation Using Meiotic Egg Extracts. Cold Spring Harb Protoc. 2018 ;2018(9):pdb.prot100958.
. Dissecting Tumor-Stromal Interactions in Breast Cancer Bone Metastasis. Endocrinol Metab (Seoul). 2016 ;31(2):206-12.
. Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion. Nat Med. 2017 ;23(2):223-234.
. Distinct -acting elements mediate targeting and clustering of polar granule mRNAs. Development. 2018 ;145(22).
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