Publications
The cell biology of aging. Mol Biol Cell. 2015 ;26(25):4524-31.
. A New Coronavirus Emerges, This Time Causing a Pandemic. Annu Rev Virol. 2020 ;7(1):iii-v.
. Reductio ad Intellectum. Annu Rev Virol. 2018 ;5(1):ii-iv.
. Optogenetic Reconstitution for Determining the Form and Function of Membraneless Organelles. Biochemistry. 2018 ;57(17):2432-2436.
. Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli. Cell Syst. 2018 ;6(6):655-663.e5.
. The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA. Mol Syst Biol. 2015 ;11(1):787.
. . Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression. Mol Cell Proteomics. 2015 ;14(9):2341-56.
. Blowing Off Steam: Virus Inhibition of cGAS DNA Sensing. Cell Host Microbe. 2015 ;18(3):270-2.
. Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease. Proc Natl Acad Sci U S A. 2018 ;115(27):E6310-E6318.
. Identification of the Intragenomic Promoter Controlling Hepatitis E Virus Subgenomic RNA Transcription. mBio. 2018 ;9(3).
. Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles. Proc Natl Acad Sci U S A. 2017 ;114(5):1147-1152.
. Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo. J Virol. 2017 ;91(4).
. A comprehensive genome-scale model for IFO0880 accounting for functional genomics and phenotypic data. Metab Eng Commun. 2019 ;9:e00101.
. The life of a microtubule. Mol Biol Cell. 2018 ;29(6):689.
. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell. 2016 ;167(7):1853-1866.e17.
. MHC class I limits hippocampal synapse density by inhibiting neuronal insulin receptor signaling. J Neurosci. 2014 ;34(35):11844-56.
. The skin microbiome of elasmobranchs follows phylosymbiosis, but in teleost fishes, the microbiomes converge. Microbiome. 2020 ;8(1):93.
. Implications of Big Data for cell biology. Mol Biol Cell. 2015 ;26(14):2575-8.
. HUMAN MICROBIOTA. Small molecules from the human microbiota. Science. 2015 ;349(6246):1254766.
. A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics. Cell. 2014 ;158(6):1402-1414.
. A Toolbox for Microbiome Engineering. Cell Syst. 2015 ;1(1):21-3.
. A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli. Nat Chem Biol. 2018 ;14(3):253-255.
. Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3. Proc Natl Acad Sci U S A. 2015 ;112(13):3949-54.
. Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1. Proc Natl Acad Sci U S A. 2013 ;110(5):1652-7.
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