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2016
Bai X-C, Yan Z, Wu J, Li Z, Yan N. The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening. Cell Res. 2016 ;26(9):995-1006.
Lee J, Xue M, Wzorek JS, Wu T, Grabowicz M, Gronenberg LS, et al. Characterization of a stalled complex on the β-barrel assembly machine. Proc Natl Acad Sci U S A. 2016 ;113(31):8717-22.
Jiang X, Smirnova I, Kasho V, Wu J, Hirata K, Ke M, et al. Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation. Proc Natl Acad Sci U S A. 2016 ;113(44):12420-12425.
Stevens AJ, Brown ZZ, Shah NH, Sekar G, Cowburn D, Muir TW. Design of a Split Intein with Exceptional Protein Splicing Activity. J Am Chem Soc. 2016 ;138(7):2162-5.
Zhou L, Holt MT, Ohashi N, Zhao A, Müller MM, Wang B, et al.. Evidence that ubiquitylated H2B corrals hDot1L on the nucleosomal surface to induce H3K79 methylation. Nat Commun. 2016 ;7:10589.
Deng D, Yan N. GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters. Protein Sci. 2016 ;25(3):546-58.
Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, et al.. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 ;167(7):1867-1882.e21.
Wang B, Muir TW. Regulation of Virulence in Staphylococcus aureus: Molecular Mechanisms and Remaining Puzzles. Cell Chem Biol. 2016 ;23(2):214-224.
Allen CD, A Link J. Self-Assembly of Catenanes from Lasso Peptides. J Am Chem Soc. 2016 ;138(43):14214-14217.
Boyaci H, Shah T, Hurley A, Kokona B, Li Z, Ventocilla C, et al. Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. PLoS Biol. 2016 ;14(5):e1002464.
Müller MM, Fierz B, Bittova L, Liszczak G, Muir TW. A two-state activation mechanism controls the histone methyltransferase Suv39h1. Nat Chem Biol. 2016 ;12(3):188-93.
2017
McCabe AL, Ricci D, Adetunji M, Silhavy TJ. Conformational Changes That Coordinate the Activity of BamA and BamD Allowing β-Barrel Assembly. J Bacteriol. 2017 ;199(20).
Ochoa A, Singh M. Domain prediction with probabilistic directional context. Bioinformatics. 2017 ;33(16):2471-2478.
Oppenheimer N, Stone HA. Effect of Hydrodynamic Interactions on Reaction Rates in Membranes. Biophys J. 2017 ;113(2):440-447.
Yan N. A Glimpse of Membrane Transport through Structures-Advances in the Structural Biology of the GLUT Glucose Transporters. J Mol Biol. 2017 ;429(17):2710-2725.
Jindal GA, Goyal Y, Humphreys JM, Yeung E, Tian K, Patterson VL, et al. How activating mutations affect MEK1 regulation and function. J Biol Chem. 2017 ;292(46):18814-18820.
Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, et al. Human CTP synthase filament structure reveals the active enzyme conformation. Nat Struct Mol Biol. 2017 ;24(6):507-514.
Ducker GS, Ghergurovich JM, Mainolfi N, Suri V, Jeong SK, Li SHsin-Jung, et al. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A. 2017 ;114(43):11404-11409.
Dann GP, Liszczak GP, Bagert JD, Müller MM, Nguyen UTT, Wojcik F, et al.. ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference. Nature. 2017 ;548(7669):607-611.
Stevens AJ, Sekar G, Shah NH, Mostafavi AZ, Cowburn D, Muir TW. A promiscuous split intein with expanded protein engineering applications. Proc Natl Acad Sci U S A. 2017 ;114(32):8538-8543.
Qian H, Zhao X, Cao P, Lei J, Yan N, Gong X. Structure of the Human Lipid Exporter ABCA1. Cell. 2017 ;169(7):1228-1239.e10.
Yan Z, Zhou Q, Wang L, Wu J, Zhao Y, Huang G, et al. Structure of the Na1.4-β1 Complex from Electric Eel. Cell. 2017 ;170(3):470-482.e11.
Davis KM, Schramma KR, Hansen WA, Bacik JP, Khare SD, Seyedsayamdost MR, et al. Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc Natl Acad Sci U S A. 2017 ;114(39):10420-10425.
Debelouchina GT, Gerecht K, Muir TW. Ubiquitin utilizes an acidic surface patch to alter chromatin structure. Nat Chem Biol. 2017 ;13(1):105-110.
2018
Hecht MH, Zarzhitsky S, Karas C, Chari S. Are natural proteins special? Can we do that?. Curr Opin Struct Biol. 2018 ;48:124-132.