Publications
Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis. ACS Chem Biol. 2016 ;11(8):2124-30.
. Quantifying Current Events Identifies a Novel Endurance Regulator. Trends Microbiol. 2016 ;24(5):324-326.
. Quorum sensing signal-response systems in Gram-negative bacteria. Nat Rev Microbiol. 2016 ;14(9):576-88.
. Regulation of Virulence in Staphylococcus aureus: Molecular Mechanisms and Remaining Puzzles. Cell Chem Biol. 2016 ;23(2):214-224.
. The Siderophore Metabolome of Azotobacter vinelandii. Appl Environ Microbiol. 2016 ;82(1):27-39.
. Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. PLoS Biol. 2016 ;14(5):e1002464.
. Vibrio cholerae biofilm growth program and architecture revealed by single-cell live imaging. Proc Natl Acad Sci U S A. 2016 ;113(36):E5337-43.
. A Burkholderia thailandensis Acyl-Homoserine Lactone-Independent Orphan LuxR Homolog That Activates Production of the Cytotoxin Malleilactone. J Bacteriol. 2015 ;197(21):3456-62.
. ComGA-RelA interaction and persistence in the Bacillus subtilis K-state. Mol Microbiol. 2015 ;97(3):454-71.
. Determinants governing ligand specificity of the Vibrio harveyi LuxN quorum-sensing receptor. Mol Microbiol. 2015 ;95(1):127-42.
. Elucidating the Specificity Determinants of the AtxE2 Lasso Peptide Isopeptidase. J Biol Chem. 2015 ;290(52):30806-12.
. Extracellular matrix structure governs invasion resistance in bacterial biofilms. ISME J. 2015 ;9(8):1700-9.
. Key driving forces in the biosynthesis of autoinducing peptides required for staphylococcal virulence. Proc Natl Acad Sci U S A. 2015 ;112(34):10679-84.
. Physics of Intracellular Organization in Bacteria. Annu Rev Microbiol. 2015 ;69:361-79.
. PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels. Science. 2015 ;349(6244):187-91.
. Crystal structure of a bacterial homologue of SWEET transporters. Cell Res. 2014 ;24(12):1486-9.
. Quorum regulatory small RNAs repress type VI secretion in Vibrio cholerae. Mol Microbiol. 2014 ;92(5):921-30.
. Analysis of the selectivity filter of the voltage-gated sodium channel Na(v)Rh. Cell Res. 2013 ;23(3):409-22.
. Dominant negative lptE mutation that supports a role for LptE as a plug in the LptD barrel. J Bacteriol. 2013 ;195(6):1327-34.
. A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proc Natl Acad Sci U S A. 2013 ;110(44):17981-6.
. Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios. PLoS Pathog. 2012 ;8(6):e1002767.
. Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel. Nature. 2012 ;486(7401):130-4.
. Ligand and antagonist driven regulation of the Vibrio cholerae quorum-sensing receptor CqsS. Mol Microbiol. 2012 ;83(6):1095-108.
. Quorum-sensing non-coding small RNAs use unique pairing regions to differentially control mRNA targets. Mol Microbiol. 2012 ;83(3):599-611.
. Recognition of methylated DNA by TAL effectors. Cell Res. 2012 ;22(10):1502-4.
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