Publications
Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles. Proc Natl Acad Sci U S A. 2017 ;114(5):1147-1152.
. Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo. J Virol. 2017 ;91(4).
. A comprehensive genome-scale model for IFO0880 accounting for functional genomics and phenotypic data. Metab Eng Commun. 2019 ;9:e00101.
. The life of a microtubule. Mol Biol Cell. 2018 ;29(6):689.
. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell. 2016 ;167(7):1853-1866.e17.
. MHC class I limits hippocampal synapse density by inhibiting neuronal insulin receptor signaling. J Neurosci. 2014 ;34(35):11844-56.
. The skin microbiome of elasmobranchs follows phylosymbiosis, but in teleost fishes, the microbiomes converge. Microbiome. 2020 ;8(1):93.
. Implications of Big Data for cell biology. Mol Biol Cell. 2015 ;26(14):2575-8.
. A Toolbox for Microbiome Engineering. Cell Syst. 2015 ;1(1):21-3.
. HUMAN MICROBIOTA. Small molecules from the human microbiota. Science. 2015 ;349(6246):1254766.
. A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics. Cell. 2014 ;158(6):1402-1414.
. A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli. Nat Chem Biol. 2018 ;14(3):253-255.
. Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3. Proc Natl Acad Sci U S A. 2015 ;112(13):3949-54.
. Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1. Proc Natl Acad Sci U S A. 2013 ;110(5):1652-7.
. Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses. Nat Commun. 2018 ;9(1):5031.
. Recent advances in understanding hepatitis C. F1000Res. 2016 ;5.
. Yellow Fever Virus: Knowledge Gaps Impeding the Fight Against an Old Foe. Trends Microbiol. 2018 ;26(11):913-928.
. A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism. PLoS Pathog. 2018 ;14(3):e1006908.
. The use of humanized mice for studies of viral pathogenesis and immunity. Curr Opin Virol. 2018 ;29:62-71.
. Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome. Nat Commun. 2017 ;8:14781.
. Type III Interferon-Mediated Signaling Is Critical for Controlling Live Attenuated Yellow Fever Virus Infection . mBio. 2017 ;8(4).
. Genetic Dissection of the Host Tropism of Human-Tropic Pathogens. Annu Rev Genet. 2015 ;49:21-45.
. Measurement of cortical elasticity in Drosophila melanogaster embryos using ferrofluids. Proc Natl Acad Sci U S A. 2017 ;114(5):1051-1056.
. Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection against Plasmodium Infection in Mice. Cell Host Microbe. 2018 ;23(4):523-535.e5.
. Architectural transitions in Vibrio cholerae biofilms at single-cell resolution. Proc Natl Acad Sci U S A. 2016 ;113(14):E2066-72.
.