Publications
Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition. Cell Res. 2015 ;25(4):401-11.
. A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors. Cell Rep. 2015 ;11(9):1486-500.
. A Systematic Ensemble Approach to Thermodynamic Modeling of Gene Expression from Sequence Data. Cell Syst. 2015 ;1(6):396-407.
. A systematic survey of the Cys2His2 zinc finger DNA-binding landscape. Nucleic Acids Res. 2015 ;43(3):1965-84.
. Searching for collective behavior in a large network of sensory neurons. PLoS Comput Biol. 2014 ;10(1):e1003408.
. Simple biochemical pathways far from steady state can provide switchlike and integrated responses. Biophys J. 2014 ;107(3):L1-L4.
. Simultaneous cellular-resolution optical perturbation and imaging of place cell firing fields. Nat Neurosci. 2014 ;17(12):1816-24.
. Social disadvantage, genetic sensitivity, and children's telomere length. Proc Natl Acad Sci U S A. 2014 ;111(16):5944-9.
. Solutions to the public goods dilemma in bacterial biofilms. Curr Biol. 2014 ;24(1):50-55.
. Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response. Science. 2014 ;343(6176):1244-8.
. Structure-activity relationships for a series of compounds that inhibit aggregation of the Alzheimer's peptide, Aβ42. Chem Biol Drug Des. 2014 ;84(5):505-12.
. subSeq: determining appropriate sequencing depth through efficient read subsampling. Bioinformatics. 2014 ;30(23):3424-6.
. A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics. Cell. 2014 ;158(6):1402-1414.
. Sec16 influences transitional ER sites by regulating rather than organizing COPII. Mol Biol Cell. 2013 ;24(21):3406-19.
. Structural advances for the major facilitator superfamily (MFS) transporters. Trends Biochem Sci. 2013 ;38(3):151-9.
. Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1. Proc Natl Acad Sci U S A. 2013 ;110(5):1652-7.
. Structural basis for the modular recognition of single-stranded RNA by PPR proteins. Nature. 2013 ;504(7478):168-71.
. Structural investigation of the proton-coupled secondary transporters. Curr Opin Struct Biol. 2013 ;23(4):483-91.
. Specific DNA-RNA hybrid recognition by TAL effectors. Cell Rep. 2012 ;2(4):707-13.
. Structural basis for sequence-specific recognition of DNA by TAL effectors. Science. 2012 ;335(6069):720-3.
. Structural basis of the unfolded protein response. Annu Rev Cell Dev Biol. 2012 ;28:251-77.
. Semi-automated atlas-based analysis of brain histological sections. J Neurosci Methods. 2011 ;196(1):12-9.
. Signal production and detection specificity in Vibrio CqsA/CqsS quorum-sensing systems. Mol Microbiol. 2011 ;79(6):1407-17.
. A small-molecule screen identifies L-kynurenine as a competitive inhibitor of TAA1/TAR activity in ethylene-directed auxin biosynthesis and root growth in Arabidopsis. Plant Cell. 2011 ;23(11):3944-60.
. A strategy for antagonizing quorum sensing. Mol Cell. 2011 ;42(2):199-209.
.