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2022
Horwitz SM, Blue TC, Ambarian JA, Hoshino S, Seyedsayamdost MR, Davis KM. Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines. RSC Chem Biol. 2022 ;3(4):420-425.
Du J, Estrella M, Solorio-Kirpichyan K, Jeffrey PD, Korennykh A. Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria. Proc Natl Acad Sci U S A. 2022 ;119(26):e2200923119.
Chen H, Zhan M, Liu J, Liu Z, Shen M, Yang F, et al. Structure-Based Design, Optimization, and Evaluation of Potent Stabilized Peptide Inhibitors Disrupting MTDH and SND1 Interaction. J Med Chem. 2022 ;65(18):12188-12199.
Pyo AGT, Zhang Y, Wingreen NS. Surface tension and super-stoichiometric surface enrichment in two-component biomolecular condensates. iScience. 2022 ;25(2):103852.
Toti KS, Jimah JR, Salmaso V, Hinshaw JE, Jacobson KA. Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin. Biomolecules. 2022 ;12(4).
Dao HT, Liu H, Mashtalir N, Kadoch C, Muir TW. Synthesis of Oriented Hexasomes and Asymmetric Nucleosomes Using a Template Editing Process. J Am Chem Soc. 2022 ;144(5):2284-2291.
McNamara HM, Ramm B, Toettcher JE. Synthetic developmental biology: New tools to deconstruct and rebuild developmental systems. Semin Cell Dev Biol. 2022 ;.
Ravindran PT, McFann S, Thornton RH, Toettcher JE. A synthetic gene circuit for imaging-free detection of signaling pulses. Cell Syst. 2022 ;13(2):131-142.e13.
Fauser F, Vilarrasa-Blasi J, Onishi M, Ramundo S, Patena W, Millican M, et al. Systematic characterization of gene function in the photosynthetic alga Chlamydomonas reinhardtii. Nat Genet. 2022 ;54(5):705-714.
2021
Valastyan JS, Kraml CM, Pelczer I, Ferrante T, Bassler BL. Saccharomyces cerevisiae Requires To Produce 4-Hydroxy-5-Methylfuran-3(2H)-One, a Mimic of the Bacterial Quorum-Sensing Autoinducer AI-2. mBio. 2021 ;12(2).
DeCandia AL, Schrom EC, Brandell EE, Stahler DR, vonHoldt BM. Sarcoptic mange severity is associated with reduced genomic variation and evidence of selection in Yellowstone National Park wolves (). Evol Appl. 2021 ;14(2):429-445.
Sanders DW, Jumper CC, Ackerman PJ, Bracha D, Donlic A, Kim H, et al. SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation. Elife. 2021 ;10.
Jemielita M, Mashruwala AA, Valastyan JS, Wingreen NS, Bassler BL. Secreted Proteases Control the Timing of Aggregative Community Formation in Vibrio cholerae. mBio. 2021 ;12(6):e0151821.
Verma A, Jena SG, Isakov DR, Aoki K, Toettcher JE, Engelhardt BE. A self-exciting point process to study multicellular spatial signaling patterns. Proc Natl Acad Sci U S A. 2021 ;118(32).
Zhang Z, TeSlaa T, Xu X, Zeng X, Yang L, Xing G, et al. Serine catabolism generates liver NADPH and supports hepatic lipogenesis. Nat Metab. 2021 ;3(12):1608-1620.
Shi C, Murphy CT. Sex and death. Curr Top Dev Biol. 2021 ;144:353-375.
García-Cañaveras JC, Lancho O, Ducker GS, Ghergurovich JM, Xu X, da Silva-Diz V, et al.. SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia. Leukemia. 2021 ;35(2):377-388.
Farahani PE, Reed EH, Underhill EJ, Aoki K, Toettcher JE. Signaling, Deconstructed: Using Optogenetics to Dissect and Direct Information Flow in Biological Systems. Annu Rev Biomed Eng. 2021 ;23:61-87.
Ruf-Zamojski F, Zhang Z, Zamojski M, Smith GR, Mendelev N, Liu H, et al. Single nucleus multi-omics regulatory landscape of the murine pituitary. Nat Commun. 2021 ;12(1):2677.
Quinn JJ, Jones MG, Okimoto RA, Nanjo S, Chan MM, Yosef N, et al. Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts. Science. 2021 ;371(6532).
Diegmiller R, Doherty CA, Stern T, Alsous JImran, Shvartsman SY. Size scaling in collective cell growth. Development. 2021 ;148(18).
Taron UH, Salado I, Escobar-Rodríguez M, Westbury MV, Butschkau S, Paijmans JLA, et al.. A sliver of the past: The decimation of the genetic diversity of the Mexican wolf. Mol Ecol. 2021 ;30(23):6340-6354.
DeCandia AL, Cassidy KA, Stahler DR, Stahler EA, vonHoldt BM. Social environment and genetics underlie body site-specific microbiomes of Yellowstone National Park gray wolves (). Ecol Evol. 2021 ;11(14):9472-9488.
TeSlaa T, Bartman CR, Jankowski CSR, Zhang Z, Xu X, Xing X, et al. The Source of Glycolytic Intermediates in Mammalian Tissues. Cell Metab. 2021 ;33(2):367-378.e5.
Huang S-K, Whitney PH, Dutta S, Shvartsman SY, Rushlow CA. Spatial organization of transcribing loci during early genome activation in Drosophila. Curr Biol. 2021 ;31(22):5102-5110.e5.