Publications
The shape of human squalene epoxidase expands the arsenal against cancer. Nat Commun. 2019 ;10(1):888.
. Scaling and shear transformations capture beak shape variation in Darwin's finches. Proc Natl Acad Sci U S A. 2010 ;107(8):3356-60.
. Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial. Pediatr Crit Care Med. 2022 ;23(10):784-792.
. Spatial organization of bacterial transcription and translation. Proc Natl Acad Sci U S A. 2016 ;113(33):9286-91.
. Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates. J Am Chem Soc. 2016 ;138(50):16452-16458.
. Selene: a PyTorch-based deep learning library for sequence data. Nat Methods. 2019 ;16(4):315-318.
. Structural Characterization and Statistical-Mechanical Model of Epidermal Patterns. Biophys J. 2016 ;111(11):2534-2545.
. A sequence-based global map of regulatory activity for deciphering human genetics. Nat Genet. 2022 ;54(7):940-949.
. A strategy for antagonizing quorum sensing. Mol Cell. 2011 ;42(2):199-209.
. Saccharomyces cerevisiae Centromere RNA Is Negatively Regulated by Cbf1 and Its Unscheduled Synthesis Impacts CenH3 Binding. Genetics. 2019 ;.
. Structure-Based Design, Optimization, and Evaluation of Potent Stabilized Peptide Inhibitors Disrupting MTDH and SND1 Interaction. J Med Chem. 2022 ;65(18):12188-12199.
. Structural identification of a bacterial quorum-sensing signal containing boron. Nature. 2002 ;415(6871):545-9.
. A systematic genetic screen for genes involved in sensing inorganic phosphate availability in Saccharomyces cerevisiae. PLoS One. 2017 ;12(5):e0176085.
. Synergy Screening Identifies a Compound That Selectively Enhances the Antibacterial Activity of Nitric Oxide. Front Bioeng Biotechnol. 2020 ;8:1001.
. Subcellular proteomics. Nat Rev Methods Primers. 2021 ;1.
. Surface association sensitizes Pseudomonas aeruginosa to quorum sensing. Nat Commun. 2019 ;10(1):4118.
. Statistical significance of variables driving systematic variation in high-dimensional data. Bioinformatics. 2015 ;31(4):545-54.
. Singing on the fly: sensorimotor integration and acoustic communication in Drosophila. Curr Opin Neurobiol. 2016 ;38:38-45.
. Sensorimotor Transformations Underlying Variability in Song Intensity during Drosophila Courtship. Neuron. 2016 ;89(3):629-44.
. The sacrificial adaptor protein Skp functions to remove stalled substrates from the β-barrel assembly machine. Proc Natl Acad Sci U S A. 2022 ;119(1).
. The structural basis of sirtuin substrate affinity. Biochemistry. 2006 ;45(24):7511-21.
. Structure of a fucose transporter in an outward-open conformation. Nature. 2010 ;467(7316):734-8.
. Synthesis of Oriented Hexasomes and Asymmetric Nucleosomes Using a Template Editing Process. J Am Chem Soc. 2022 ;144(5):2284-2291.
. Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc Natl Acad Sci U S A. 2017 ;114(39):10420-10425.
. Social environment and genetics underlie body site-specific microbiomes of Yellowstone National Park gray wolves (). Ecol Evol. 2021 ;11(14):9472-9488.
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