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2021
Cho S, Lee G, Pickering BF, Jang C, Park JH, He L, et al. mTORC1 promotes cell growth via mA-dependent mRNA degradation. Mol Cell. 2021 ;81(10):2064-2075.e8.
Garrison CM, Singh-Varma A, Pastino AK, Steele JAM, Kohn J, N Murthy S, et al. A multilayered scaffold for regeneration of smooth muscle and connective tissue layers. J Biomed Mater Res A. 2021 ;109(5):733-744.
El-Achkar TM, Eadon MT, Menon R, Lake BB, Sigdel TK, Alexandrov T, et al. A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: guidelines from the Kidney Precision Medicine Project. Physiol Genomics. 2021 ;53(1):1-11.
Arlow T, Kim J, Haye-Bertolozzi JE, Martínez CBalbás, Fay C, Zorensky E, et al.. MutSα mismatch repair protein stability is governed by subunit interaction, acetylation, and ubiquitination. G3 (Bethesda). 2021 ;11(3).
2020
Sealfon RSG, Mariani LH, Kretzler M, Troyanskaya OG. Machine learning, the kidney, and genotype-phenotype analysis. Kidney Int. 2020 ;97(6):1141-1149.
Forneris CC, Nguy AKL, Seyedsayamdost MR. Mapping and Exploiting the Promiscuity of OxyB toward the Biocatalytic Production of Vancomycin Aglycone Variants. ACS Catal. 2020 ;10(16):9287-9298.
Sargin D, Chottekalapanda RU, Perit KE, Yao V, Chu D, Sparks DW, et al. Mapping the physiological and molecular markers of stress and SSRI antidepressant treatment in S100a10 corticostriatal neurons. Mol Psychiatry. 2020 ;25(5):1112-1129.
Nerger BA, Brun P-T, Nelson CM. Marangoni flows drive the alignment of fibrillar cell-laden hydrogels. Sci Adv. 2020 ;6(24):eaaz7748.
Ackerman CM, Myhrvold C, Thakku SGowtham, Freije CA, Metsky HC, Yang DK, et al. Massively multiplexed nucleic acid detection with Cas13. Nature. 2020 ;582(7811):277-282.
Maya S, Ploss A. Master of Disguise: Hepatitis Delta Virus Packaging and Spread Facilitated by Diverse Viral Envelope Proteins. Hepatology. 2020 ;71(1):380-382.
Tien J, Ghani U, Dance YW, Seibel AJ, M Karakan Ç, Ekinci KL, et al.. Matrix Pore Size Governs Escape of Human Breast Cancer Cells from a Microtumor to an Empty Cavity. iScience. 2020 ;23(11):101673.
Kinoshita N, Hashimoto Y, Yasue N, Suzuki M, Cristea IM, Ueno N. Mechanical Stress Regulates Epithelial Tissue Integrity and Stiffness through the FGFR/Erk2 Signaling Pathway during Embryogenesis. Cell Rep. 2020 ;30(11):3875-3888.e3.
Fiore VF, Krajnc M, Quiroz FGarcia, Levorse J, H Pasolli A, Shvartsman SY, et al. Mechanics of a multilayer epithelium instruct tumour architecture and function. Nature. 2020 ;585(7825):433-439.
Huang X, Duddy OP, Silpe JE, Paczkowski JE, Cong J, Henke BR, et al. Mechanism underlying autoinducer recognition in the DPO-VqmA quorum-sensing pathway. J Biol Chem. 2020 ;295(10):2916-2931.
Green R, Wang L, Hart SFM, Lu W, Skelding D, Burton JC, et al. Metabolic excretion associated with nutrient-growth dysregulation promotes the rapid evolution of an overt metabolic defect. PLoS Biol. 2020 ;18(8):e3000757.
Liou CS, Sirk SJ, Diaz CAC, Klein AP, Fischer CR, Higginbottom SK, et al. A Metabolic Pathway for Activation of Dietary Glucosinolates by a Human Gut Symbiont. Cell. 2020 ;180(4):717-728.e19.
Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, et al. Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Mol Cancer Res. 2020 ;18(4):599-611.
Mor DE, Sohrabi S, Kaletsky R, Keyes W, Tartici A, Kalia V, et al. Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria. Proc Natl Acad Sci U S A. 2020 ;117(42):26438-26447.
Chen Y-C, Seyedsayamdost MR, Ringstad N. A microbial metabolite synergizes with endogenous serotonin to trigger reproductive behavior. Proc Natl Acad Sci U S A. 2020 ;117(48):30589-30598.
Federspiel JD, Cook KC, Kennedy MA, Venkatesh SS, Otter CJ, Hofstadter WA, et al. Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA. Cell Rep. 2020 ;32(4):107943.
Hammer SK, Zhang Y, Avalos JL. Mitochondrial Compartmentalization Confers Specificity to the 2-Ketoacid Recursive Pathway: Increasing Isopentanol Production in . ACS Synth Biol. 2020 ;9(3):546-555.
Mor DE, Murphy CT. Mitochondrial hyperactivity as a potential therapeutic target in Parkinson's disease. Transl Med Aging. 2020 ;4:117-120.
Statt A, Casademunt H, Brangwynne CP, Panagiotopoulos AZ. Model for disordered proteins with strongly sequence-dependent liquid phase behavior. J Chem Phys. 2020 ;152(7):075101.
Li Z, Liu B, Li SHsin-Jung, King CG, Gitai Z, Wingreen NS. Modeling microbial metabolic trade-offs in a chemostat. PLoS Comput Biol. 2020 ;16(8):e1008156.
Graim K, Gorenshteyn D, Robinson DG, Carriero NJ, Cahill JA, Chakrabarti R, et al. Modeling molecular development of breast cancer in canine mammary tumors. Genome Res. 2020 ;.