Publications
Mitotic internalization of planar cell polarity proteins preserves tissue polarity. Nat Cell Biol. 2011 ;13(8):893-902.
. The cell biology of aging. Mol Biol Cell. 2015 ;26(25):4524-31.
. A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli. Nat Chem Biol. 2018 ;14(3):253-255.
. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metab. 2016 ;23(6):1140-1153.
. Enzyme regulation and mutation in a model serial-dilution ecosystem. Phys Rev E. 2021 ;104(4-1):044412.
. Methionine synthase supports tumour tetrahydrofolate pools. Nat Metab. 2021 ;3(11):1512-1520.
. Common and divergent features of galactose-1-phosphate and fructose-1-phosphate toxicity in yeast. Mol Biol Cell. 2018 ;29(8):897-910.
. Parallel imaging of embryos for quantitative analysis of genetic perturbations of the Ras pathway. Dis Model Mech. 2017 ;10(7):923-929.
. Dominant negative lptE mutation that supports a role for LptE as a plug in the LptD barrel. J Bacteriol. 2013 ;195(6):1327-34.
. Zebrafish models of idiopathic scoliosis link cerebrospinal fluid flow defects to spine curvature. Science. 2016 ;352(6291):1341-4.
. C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation. Nat Commun. 2015 ;6:8919.
. Fine-Tuning of σ Activation Suppresses Multiple Assembly-Defective Mutations in Escherichia coli. J Bacteriol. 2019 ;201(11).
. Functions of the BamBCDE Lipoproteins Revealed by Bypass Mutations in BamA. J Bacteriol. 2020 ;202(21).
. Flow-dependent myosin recruitment during Drosophila cellularization requires zygotic dunk activity. Development. 2016 ;143(13):2417-30.
. PQM-1 controls hypoxic survival via regulation of lipid metabolism. Nat Commun. 2020 ;11(1):4627.
. CCDC151 mutations cause primary ciliary dyskinesia by disruption of the outer dynein arm docking complex formation. Am J Hum Genet. 2014 ;95(3):257-74.
. Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin. Proc Natl Acad Sci U S A. 2015 ;112(33):10365-70.
. Network-Based Coverage of Mutational Profiles Reveals Cancer Genes. Cell Syst. 2017 ;5(3):221-229.e4.
. Structure-based assessment of disease-related mutations in human voltage-gated sodium channels. Protein Cell. 2017 ;8(6):401-438.
. A Rubisco-binding protein is required for normal pyrenoid number and starch sheath morphology in . Proc Natl Acad Sci U S A. 2019 ;116(37):18445-18454.
. c21orf59/kurly Controls Both Cilia Motility and Polarization. Cell Rep. 2016 ;14(8):1841-9.
. Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase. Proc Natl Acad Sci U S A. 2019 ;116(17):8295-8300.
. HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome. Proc Natl Acad Sci U S A. 2018 ;115(5):E876-E885.
. Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation. Proc Natl Acad Sci U S A. 2016 ;113(44):12420-12425.
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