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Author Title [ Year(Desc)]
Filters: Keyword is Cryoelectron Microscopy  [Clear All Filters]
2020
Yao X, Fan X, Yan N. Cryo-EM analysis of a membrane protein embedded in the liposome. Proc Natl Acad Sci U S A. 2020 ;117(31):18497-18503.
Gao S, Valinsky WC, On NCam, Houlihan PR, Qu Q, Liu L, et al. Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na channels in nanodisc. Proc Natl Acad Sci U S A. 2020 ;117(25):14187-14193.
Qian H, Zhao X, Yan R, Yao X, Gao S, Sun X, et al. Structural basis for catalysis and substrate specificity of human ACAT1. Nature. 2020 ;581(7808):333-338.
Pan Y, Ren Z, Gao S, Shen J, Wang L, Xu Z, et al. Structural basis of ion transport and inhibition in ferroportin. Nat Commun. 2020 ;11(1):5686.
Wang L, Qian H, Nian Y, Han Y, Ren Z, Zhang H, et al. Structure and mechanism of human diacylglycerol O-acyltransferase 1. Nature. 2020 ;581(7808):329-332.
2021
Pan X, Li Z, Jin X, Zhao Y, Huang G, Huang X, et al. Comparative structural analysis of human Na1.1 and Na1.5 reveals mutational hotspots for sodium channelopathies. Proc Natl Acad Sci U S A. 2021 ;118(11).
Li Z, Jin X, Wu T, Huang G, Wu K, Lei J, et al. Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Na 1.5 by the Antiarrhythmic Drug Quinidine*. Angew Chem Int Ed Engl. 2021 ;60(20):11474-11480.
Gong D, Yan N, Ledford HA. Structural Basis for the Modulation of Ryanodine Receptors. Trends Biochem Sci. 2021 ;46(6):489-501.
Gao S, Yan N. Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Ca 1.1 by Dihydropyridine Compounds*. Angew Chem Int Ed Engl. 2021 ;60(6):3131-3137.
Shen H, Yan N, Pan X. Structural determination of human Na v 1.4 and Na v 1.7 using single particle cryo-electron microscopy. Methods Enzymol. 2021 ;653:103-120.
Gao S, Yao X, Yan N. Structure of human Ca2.2 channel blocked by the painkiller ziconotide. Nature. 2021 ;596(7870):143-147.
Li Z, Jin X, Wu T, Zhao X, Wang W, Lei J, et al. Structure of human Na1.5 reveals the fast inactivation-related segments as a mutational hotspot for the long QT syndrome. Proc Natl Acad Sci U S A. 2021 ;118(11).
Yan R, Cao P, Song W, Qian H, Du X, Coates HW, et al. A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols. Science. 2021 ;371(6533).