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Cho S, Lee G, Pickering BF, Jang C, Park JH, He L, et al. mTORC1 promotes cell growth via mA-dependent mRNA degradation. Mol Cell. 2021 ;81(10):2064-2075.e8.
Schild T, McReynolds MR, Shea C, Low V, Schaffer BE, Asara JM, et al. NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma. Cell Rep. 2021 ;35(11):109238.
Basta LP, Hill-Oliva M, Paramore SV, Sharan R, Goh A, Biswas A, et al. New mouse models for high resolution and live imaging of planar cell polarity proteins in vivo. Development. 2021 ;148(18).
Zhao EM, Lalwani MA, Chen J-M, Orillac P, Toettcher JE, Avalos JL. Optogenetic Amplification Circuits for Light-Induced Metabolic Control. ACS Synth Biol. 2021 ;10(5):1143-1154.
Dine E, Reed EH, Toettcher JE. Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch. Cell Rep. 2021 ;35(12):109280.
Song B, Liu D, Greco TM, Cristea IM. Post-translational modification control of viral DNA sensors and innate immune signaling. Adv Virus Res. 2021 ;109:163-199.
Seath CP, Trowbridge AD, Muir TW, MacMillan DWC. Reactive intermediates for interactome mapping. Chem Soc Rev. 2021 ;50(5):2911-2926.
Lee Y, Jung Y, Jeong D-E, Hwang W, Ham S, Park H-EH, et al. Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop. J Cell Biol. 2021 ;220(5).
Minhas PS, Latif-Hernandez A, McReynolds MR, Durairaj AS, Wang Q, Rubin A, et al. Restoring metabolism of myeloid cells reverses cognitive decline in ageing. Nature. 2021 ;590(7844):122-128.
Valastyan JS, Kraml CM, Pelczer I, Ferrante T, Bassler BL. Saccharomyces cerevisiae Requires To Produce 4-Hydroxy-5-Methylfuran-3(2H)-One, a Mimic of the Bacterial Quorum-Sensing Autoinducer AI-2. mBio. 2021 ;12(2).
Verma A, Jena SG, Isakov DR, Aoki K, Toettcher JE, Engelhardt BE. A self-exciting point process to study multicellular spatial signaling patterns. Proc Natl Acad Sci U S A. 2021 ;118(32).
Farahani PE, Reed EH, Underhill EJ, Aoki K, Toettcher JE. Signaling, Deconstructed: Using Optogenetics to Dissect and Direct Information Flow in Biological Systems. Annu Rev Biomed Eng. 2021 ;23:61-87.
Farahani PE, Lemke SB, Dine E, Uribe G, Toettcher JE, Nelson CM. Substratum stiffness regulates Erk signaling dynamics through receptor-level control. Cell Rep. 2021 ;37(13):110181.
Rabie EM, Zhang SX, Dunn CE, Nelson CM. Substratum stiffness signals through integrin-linked kinase and β1-integrin to regulate midbody proteins and abscission during EMT. Mol Biol Cell. 2021 ;32(18):1664-1676.
Paul S, Yang L, Mattingly H, Goyal Y, Shvartsman SY, Veraksa A. Activation-induced substrate engagement in ERK signaling. Mol Biol Cell. 2020 ;31(4):235-243.
Goodwin K, Nelson CM. Branching morphogenesis. Development. 2020 ;147(10).
Templeman NM, Cota V, Keyes W, Kaletsky R, Murphy CT. CREB Non-autonomously Controls Reproductive Aging through Hedgehog/Patched Signaling. Dev Cell. 2020 ;54(1):92-105.e5.
Vrla GD, Esposito M, Zhang C, Kang Y, Seyedsayamdost MR, Gitai Z. Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa. PLoS Pathog. 2020 ;16(9):e1008867.
Song B, Greco TM, Lum KK, Taber CE, Cristea IM. The DNA Sensor cGAS is Decorated by Acetylation and Phosphorylation Modifications in the Context of Immune Signaling. Mol Cell Proteomics. 2020 ;19(7):1193-1208.
Ravindran PT, Wilson MZ, Jena SG, Toettcher JE. Engineering combinatorial and dynamic decoders using synthetic immediate-early genes. Commun Biol. 2020 ;3(1):436.
Bridges AA, Fei C, Bassler BL. Identification of signaling pathways, matrix-digestion enzymes, and motility components controlling biofilm dispersal. Proc Natl Acad Sci U S A. 2020 ;117(51):32639-32647.
Grimes DT, Patterson VL, Luna-Arvizu G, Schottenfeld-Roames J, Irons ZH, Burdine RD. Left-right asymmetric heart jogging increases the robustness of dextral heart looping in zebrafish. Dev Biol. 2020 ;459(2):79-86.
Goglia AG, Wilson MZ, Jena SG, Silbert J, Basta LP, Devenport D, et al. A Live-Cell Screen for Altered Erk Dynamics Reveals Principles of Proliferative Control. Cell Syst. 2020 ;10(3):240-253.e6.
Kinoshita N, Hashimoto Y, Yasue N, Suzuki M, Cristea IM, Ueno N. Mechanical Stress Regulates Epithelial Tissue Integrity and Stiffness through the FGFR/Erk2 Signaling Pathway during Embryogenesis. Cell Rep. 2020 ;30(11):3875-3888.e3.
Huang X, Duddy OP, Silpe JE, Paczkowski JE, Cong J, Henke BR, et al. Mechanism underlying autoinducer recognition in the DPO-VqmA quorum-sensing pathway. J Biol Chem. 2020 ;295(10):2916-2931.