Publications
Structural determinants driving homoserine lactone ligand selection in the LasR quorum-sensing receptor. Proc Natl Acad Sci U S A. 2019 ;116(1):245-254.
. Surface association sensitizes Pseudomonas aeruginosa to quorum sensing. Nat Commun. 2019 ;10(1):4118.
. Charting an Unexplored Streptococcal Biosynthetic Landscape Reveals a Unique Peptide Cyclization Motif. J Am Chem Soc. 2018 ;140(50):17674-17684.
. Malleilactone Is a Burkholderia pseudomallei Virulence Factor Regulated by Antibiotics and Quorum Sensing. J Bacteriol. 2018 ;200(14).
. The PqsE and RhlR proteins are an autoinducer synthase-receptor pair that control virulence and biofilm development in . Proc Natl Acad Sci U S A. 2018 ;115(40):E9411-E9418.
. Quorum sensing and iron regulate a two-for-one siderophore gene cluster in . Proc Natl Acad Sci U S A. 2018 ;115(29):7581-7586.
. Quorum sensing controls multicellular aggregate formation. Elife. 2018 ;7.
. SnapShot: Bacterial Quorum Sensing. Cell. 2018 ;174(5):1328-1328.e1.
. Asymmetric regulation of quorum-sensing receptors drives autoinducer-specific gene expression programs in Vibrio cholerae. PLoS Genet. 2017 ;13(5):e1006826.
. Flavonoids Suppress Virulence through Allosteric Inhibition of Quorum-sensing Receptors. J Biol Chem. 2017 ;292(10):4064-4076.
. Functional Plasticity of the AgrC Receptor Histidine Kinase Required for Staphylococcal Virulence. Cell Chem Biol. 2017 ;24(1):76-86.
. Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system. Proc Natl Acad Sci U S A. 2017 ;114(1):131-135.
. The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer. PLoS Pathog. 2017 ;13(7):e1006504.
. Surface-attached molecules control Staphylococcus aureus quorum sensing and biofilm development. Nat Microbiol. 2017 ;2:17080.
. A Vibrio cholerae autoinducer-receptor pair that controls biofilm formation. Nat Chem Biol. 2017 ;13(5):551-557.
. A Host-Produced Autoinducer-2 Mimic Activates Bacterial Quorum Sensing. Cell Host Microbe. 2016 ;19(4):470-80.
. Investigation of the Genetics and Biochemistry of Roseobacticide Production in the Roseobacter Clade Bacterium Phaeobacter inhibens. mBio. 2016 ;7(2):e02118.
. Local and global consequences of flow on bacterial quorum sensing. Nat Microbiol. 2016 ;1:15005.
. Quorum sensing signal-response systems in Gram-negative bacteria. Nat Rev Microbiol. 2016 ;14(9):576-88.
. Social Evolution Selects for Redundancy in Bacterial Quorum Sensing. PLoS Biol. 2016 ;14(2):e1002386.
. Comprehensive analysis reveals how single nucleotides contribute to noncoding RNA function in bacterial quorum sensing. Proc Natl Acad Sci U S A. 2015 ;112(44):E6038-47.
. Determinants governing ligand specificity of the Vibrio harveyi LuxN quorum-sensing receptor. Mol Microbiol. 2015 ;95(1):127-42.
. Key driving forces in the biosynthesis of autoinducing peptides required for staphylococcal virulence. Proc Natl Acad Sci U S A. 2015 ;112(34):10679-84.
. A qrr noncoding RNA deploys four different regulatory mechanisms to optimize quorum-sensing dynamics. Cell. 2015 ;160(1-2):228-40.
. Quorum sensing regulates the osmotic stress response in Vibrio harveyi. J Bacteriol. 2015 ;197(1):73-80.
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