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2022
Qin Y, Kernan KF, Fan Z, Park H-J, Kim S, Canna SW, et al. Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials. Crit Care. 2022 ;26(1):128.
Shekhtman L, Cotler SJ, Ploss A, Dahari H. Mathematical modeling suggests that entry-inhibitor bulevirtide may interfere with hepatitis D virus clearance from circulation. J Hepatol. 2022 ;76(5):1229-1231.
Overman KE, Choi DM, Leung K, Shaevitz JW, Berman GJ. Measuring the repertoire of age-related behavioral changes in Drosophila melanogaster. PLoS Comput Biol. 2022 ;18(2):e1009867.
Nelson CM. Mechanical Control of Cell Differentiation: Insights from the Early Embryo. Annu Rev Biomed Eng. 2022 ;24:307-322.
Singh J, Alsous JImran, Garikipati K, Shvartsman SY. Mechanics of stabilized intercellular bridges. Biophys J. 2022 ;121(16):3162-3171.
Lee DSW, Strom AR, Brangwynne CP. The mechanobiology of nuclear phase separation. APL Bioeng. 2022 ;6(2):021503.
Landajuela A, Braun M, Martínez-Calvo A, Rodrigues CDA, Perez CGomis, Doan T, et al.. Membrane fission during bacterial spore development requires cellular inflation driven by DNA translocation. Curr Biol. 2022 ;.
Jang C, Hui S, Zeng X, Cowan AJ, Wang L, Chen L, et al. Metabolite Exchange between Mammalian Organs Quantified in Pigs. Cell Metab. 2022 ;34(9):1410.
Tang Y, Kang Y. Microbial metabolite as icebreaker for immunotherapy. Cell Metab. 2022 ;34(4):506-507.
Fei C, Wilson AT, Mangan NM, Wingreen NS, Jonikas MC. Modelling the pyrenoid-based CO-concentrating mechanism provides insights into its operating principles and a roadmap for its engineering into crops. Nat Plants. 2022 ;8(5):583-595.
Wang N, Zhang S, Yuan Y, Xu H, Defossa E, Matter H, et al. Molecular basis for inhibiting human glucose transporters by exofacial inhibitors. Nat Commun. 2022 ;13(1):2632.
Liu Y, Park D, Cafiero TR, Bram Y, Chandar V, Tseng A, et al. Molecular clones of genetically distinct hepatitis B virus genotypes reveal distinct host and drug treatment responses. JHEP Rep. 2022 ;4(9):100535.
Li Y, Lee SRak, Han EJ, Seyedsayamdost MR. Momomycin, an Antiproliferative Cryptic Metabolite from the Oxytetracycline Producer Streptomyces rimosus. Angew Chem Int Ed Engl. 2022 ;61(39):e202208573.
Zhao Z, Zung JL, Hinze A, Kriete AL, Iqbal A, Younger MA, et al. Mosquito brains encode unique features of human odour to drive host seeking. Nature. 2022 ;605(7911):706-712.
Sugiura A, Andrejeva G, Voss K, Heintzman DR, Xu X, Madden MZ, et al. MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function. Immunity. 2022 ;55(1):65-81.e9.
Zhang P, Chan MM. A multifaceted signal recorder of cellular experiences using Cas12a base-editing. Trends Biotechnol. 2022 ;.
Welch NL, Zhu M, Hua C, Weller J, Mirhashemi MEzzaty, Nguyen TG, et al. Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants. Nat Med. 2022 ;28(5):1083-1094.
Thakku SGowtham, Ackerman CM, Myhrvold C, Bhattacharyya RP, Livny J, Ma P, et al. Multiplexed detection of bacterial nucleic acids using Cas13 in droplet microarrays. PNAS Nexus. 2022 ;1(1):pgac021.
2021
Tkačik G, Gregor T. The many bits of positional information. Development. 2021 ;148(2).
Postika N, Schedl P, Georgiev P, Kyrchanova O. Mapping of functional elements of the Fab-6 boundary involved in the regulation of the Abd-B hox gene in Drosophila melanogaster. Sci Rep. 2021 ;11(1):4156.
Diegmiller R, Zhang L, Gameiro M, Barr J, Alsous JImran, Schedl P, et al. Mapping parameter spaces of biological switches. PLoS Comput Biol. 2021 ;17(2):e1008711.
Hussmann JA, Ling J, Ravisankar P, Yan J, Cirincione A, Xu A, et al. Mapping the genetic landscape of DNA double-strand break repair. Cell. 2021 ;184(22):5653-5669.e25.
Rabie EM, Zhang SX, Kourouklis AP, A Kilinc N, Simi AK, Radisky DC, et al. Matrix degradation and cell proliferation are coupled to promote invasion and escape from an engineered human breast microtumor. Integr Biol (Camb). 2021 ;13(1):17-29.
Willgoss T, Cassater D, Connor S, Krishnan ML, Miller MT, Dias-Barbosa C, et al. Measuring What Matters to Individuals with Angelman Syndrome and Their Families: Development of a Patient-Centered Disease Concept Model. Child Psychiatry Hum Dev. 2021 ;52(4):654-668.
Zhang Y, Lee DSW, Meir Y, Brangwynne CP, Wingreen NS. Mechanical Frustration of Phase Separation in the Cell Nucleus by Chromatin. Phys Rev Lett. 2021 ;126(25):258102.