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2022
Doyle MThomas, Jimah JR, Dowdy T, Ohlemacher SI, Larion M, Hinshaw JE, et al. Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding. Cell. 2022 ;185(7):1143-1156.e13.
Combs AN, Silhavy TJ. The sacrificial adaptor protein Skp functions to remove stalled substrates from the β-barrel assembly machine. Proc Natl Acad Sci U S A. 2022 ;119(1).
2021
Guest RL, Rutherford ST, Silhavy TJ. Border Control: Regulating LPS Biogenesis. Trends Microbiol. 2021 ;29(4):334-345.
Benn G, Mikheyeva IV, Inns PGeorge, Forster JC, Ojkic N, Bortolini C, et al. Phase separation in the outer membrane of . Proc Natl Acad Sci U S A. 2021 ;118(44).
Murawski AM, Brynildsen MP. Ploidy is an important determinant of fluoroquinolone persister survival. Curr Biol. 2021 ;31(10):2039-2050.e7.
Seath CP, Trowbridge AD, Muir TW, MacMillan DWC. Reactive intermediates for interactome mapping. Chem Soc Rev. 2021 ;50(5):2911-2926.
Wan X, Brynildsen MP. Robustness of nitric oxide detoxification to nitrogen starvation in Escherichia coli requires RelA. Free Radic Biol Med. 2021 ;176:286-297.
2020
Werner JN, Shi H, Hsin J, Huang KCasey, Gitai Z, Klein EA. AimB Is a Small Protein Regulator of Cell Size and MreB Assembly. Biophys J. 2020 ;119(3):593-604.
Yao X, Fan X, Yan N. Cryo-EM analysis of a membrane protein embedded in the liposome. Proc Natl Acad Sci U S A. 2020 ;117(31):18497-18503.
Hart EM, Silhavy TJ. Functions of the BamBCDE Lipoproteins Revealed by Bypass Mutations in BamA. J Bacteriol. 2020 ;202(21).
Hart EM, Gupta M, Wühr M, Silhavy TJ. The gain-of-function allele bypasses the essential requirement for BamD in β-barrel outer membrane protein assembly. Proc Natl Acad Sci U S A. 2020 ;117(31):18737-18743.
Grimm J, Shi H, Wang W, Mitchell AM, Wingreen NS, Huang KCasey, et al. The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow in . Proc Natl Acad Sci U S A. 2020 ;117(43):26907-26914.
Guest RL, Guerra DSamé, Wissler M, Grimm J, Silhavy TJ. YejM Modulates Activity of the YciM/FtsH Protease Complex To Prevent Lethal Accumulation of Lipopolysaccharide. mBio. 2020 ;11(2).
2019
Stubbe JA, Seyedsayamdost MR. Discovery of a New Class I Ribonucleotide Reductase with an Essential DOPA Radical and NO Metal as an Initiator of Long-Range Radical Transfer. Biochemistry. 2019 ;58(6):435-437.
Barrett TC, Mok WWK, Murawski AM, Brynildsen MP. Enhanced antibiotic resistance development from fluoroquinolone persisters after a single exposure to antibiotic. Nat Commun. 2019 ;10(1):1177.
Hart EM, O'Connell A, Tang K, Wzorek JS, Grabowicz M, Kahne D, et al. Fine-Tuning of σ Activation Suppresses Multiple Assembly-Defective Mutations in Escherichia coli. J Bacteriol. 2019 ;201(11).
Silhavy TJ, Mitchell AM. Genetic Analysis of Protein Translocation. Protein J. 2019 ;38(3):217-228.
Chou WKang, Brynildsen MP. Loss of DksA leads to multi-faceted impairment of nitric oxide detoxification by Escherichia coli. Free Radic Biol Med. 2019 ;130:288-296.
Ricci DP, Silhavy TJ. Outer Membrane Protein Insertion by the β-barrel Assembly Machine. EcoSal Plus. 2019 ;8(2).
Hart EM, Mitchell AM, Konovalova A, Grabowicz M, Sheng J, Han X, et al. A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier. Proc Natl Acad Sci U S A. 2019 ;116(43):21748-21757.
Aedo SJ, Orman MA, Brynildsen MP. Stationary phase persister formation in Escherichia coli can be suppressed by piperacillin and PBP3 inhibition. BMC Microbiol. 2019 ;19(1):140.
Hart EM, Gupta M, Wühr M, Silhavy TJ. The Synthetic Phenotype of Δ Δ Double Mutants Results from a Lethal Jamming of the Bam Complex by the Lipoprotein RcsF. mBio. 2019 ;10(3).
Adolfsen KJ, Chou WKang, Brynildsen MP. Transcriptional Regulation Contributes to Prioritized Detoxification of Hydrogen Peroxide over Nitric Oxide. J Bacteriol. 2019 ;201(14).
Schober AF, Mathis AD, Ingle C, Park JO, Chen L, Rabinowitz JD, et al. A Two-Enzyme Adaptive Unit within Bacterial Folate Metabolism. Cell Rep. 2019 ;27(11):3359-3370.e7.
2018
Hecht MH, Zarzhitsky S, Karas C, Chari S. Are natural proteins special? Can we do that?. Curr Opin Struct Biol. 2018 ;48:124-132.