Publications
The structure and spontaneous curvature of clathrin lattices at the plasma membrane. Dev Cell. 2021 ;56(8):1131-1146.e3.
. Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2. Cell. 2020 ;182(1):98-111.e18.
. Structural basis for the recognition of Sonic Hedgehog by human Patched1. Science. 2018 ;361(6402).
. Shape Transformations of Lipid Bilayers Following Rapid Cholesterol Uptake. Biophys J. 2016 ;111(12):2651-2657.
. The shape of human squalene epoxidase expands the arsenal against cancer. Nat Commun. 2019 ;10(1):888.
. . Role of the ABC transporter Mdr49 in Hedgehog signaling and germ cell migration. Development. 2016 ;143(12):2111-20.
. Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling. Cell. 2017 ;171(7):1545-1558.e18.
. Mapping the Genetic Landscape of Human Cells. Cell. 2018 ;174(4):953-967.e22.
. Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm. Nat Commun. 2019 ;10(1):2320.
. Cells on the move: Modulation of guidance cues during germ cell migration. Fly (Austin). 2017 ;11(3):200-207.
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