Publications
Monitoring mammalian mitochondrial translation with MitoRiboSeq. Nat Protoc. 2021 ;16(6):2802-2825.
. Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis. Cancer Res. 2020 ;80(18):3820-3829.
. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Nat Chem Biol. 2020 ;16(7):731-739.
. NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism. Nat Metab. 2019 ;1:404-415.
. Mitochondrial translation requires folate-dependent tRNA methylation. Nature. 2018 ;554(7690):128-132.
. Quantitative Analysis of NAD Synthesis-Breakdown Fluxes. Cell Metab. 2018 ;27(5):1067-1080.e5.
. Chemical Basis for Deuterium Labeling of Fat and NADPH. J Am Chem Soc. 2017 ;139(41):14368-14371.
. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metab. 2016 ;23(6):1140-1153.
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