Publications
Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme. Mol Cell. 2005 ;17(6):855-68.
. Multiple signalling systems controlling expression of luminescence in Vibrio harveyi: sequence and function of genes encoding a second sensory pathway. Mol Microbiol. 1994 ;13(2):273-86.
. Sequence and function of LuxO, a negative regulator of luminescence in Vibrio harveyi. Mol Microbiol. 1994 ;12(3):403-12.
. Intercellular signalling in Vibrio harveyi: sequence and function of genes regulating expression of luminescence. Mol Microbiol. 1993 ;9(4):773-86.
. An intein-based genetic selection allows the construction of a high-quality library of binary patterned de novo protein sequences. Protein Eng Des Sel. 2005 ;18(4):201-7.
. Protein reconstitution and three-dimensional domain swapping: benefits and constraints of covalency. Protein Sci. 2007 ;16(11):2317-33.
. Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress. Mol Cell. 2012 ;47(3):396-409.
. The structural basis of sirtuin substrate affinity. Biochemistry. 2006 ;45(24):7511-21.
. orco mutant mosquitoes lose strong preference for humans and are not repelled by volatile DEET. Nature. 2013 ;498(7455):487-91.
. Revisiting the TALE repeat. Protein Cell. 2014 ;5(4):297-306.
. Structural basis for sequence-specific recognition of DNA by TAL effectors. Science. 2012 ;335(6069):720-3.
. A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics. Cell. 2014 ;158(6):1402-1414.
. Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1. Proc Natl Acad Sci U S A. 2013 ;110(5):1652-7.
. Mapping the binding interface of ERK and transcriptional repressor Capicua using photocrosslinking. Proc Natl Acad Sci U S A. 2015 ;112(28):8590-5.
. Innate immune messenger 2-5A tethers human RNase L into active high-order complexes. Cell Rep. 2012 ;2(4):902-13.
. The molecular basis of ABA-independent inhibition of PP2Cs by a subclass of PYL proteins. Mol Cell. 2011 ;42(5):662-72.
. Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin. Proc Natl Acad Sci U S A. 2015 ;112(33):10365-70.
. Evidence for a signaling system in Helicobacter pylori: detection of a luxS-encoded autoinducer. J Bacteriol. 2000 ;182(13):3638-43.
. The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae. Cell. 2004 ;118(1):69-82.
. Examination of the dimerization states of the single-stranded RNA recognition protein pentatricopeptide repeat 10 (PPR10). J Biol Chem. 2014 ;289(45):31503-12.
. Molecular basis for the selective and ABA-independent inhibition of PP2CA by PYL13. Cell Res. 2013 ;23(12):1369-79.
. Regulation of quorum sensing in Vibrio harveyi by LuxO and sigma-54. Mol Microbiol. 2000 ;36(4):940-54.
. Biosynthesis: Leading the way to RiPPs. Nat Chem Biol. 2015 ;11(8):551-2.
. Elucidating the Specificity Determinants of the AtxE2 Lasso Peptide Isopeptidase. J Biol Chem. 2015 ;290(52):30806-12.
. Salmonella typhimurium recognizes a chemically distinct form of the bacterial quorum-sensing signal AI-2. Mol Cell. 2004 ;15(5):677-87.
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