Publications
Are natural proteins special? Can we do that?. Curr Opin Struct Biol. 2018 ;48:124-132.
. A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens. Nat Methods. 2012 ;9(4):363-6.
. A de novo protein confers copper resistance in Escherichia coli. Protein Sci. 2016 ;25(7):1249-59.
. Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2. Genes Dev. 2020 ;34(19-20):1310-1315.
. . A genome-scale yeast library with inducible expression of individual genes. Mol Syst Biol. 2021 ;17(6):e10207.
. A genome-wide algal mutant library and functional screen identifies genes required for eukaryotic photosynthesis. Nat Genet. 2019 ;51(4):627-635.
. An Indexed, Mapped Mutant Library Enables Reverse Genetics Studies of Biological Processes in Chlamydomonas reinhardtii. Plant Cell. 2016 ;28(2):367-87.
. An intein-based genetic selection allows the construction of a high-quality library of binary patterned de novo protein sequences. Protein Eng Des Sel. 2005 ;18(4):201-7.
. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nat Chem Biol. 2021 ;17(4):403-411.
. Rapid construction of a whole-genome transposon insertion collection for Shewanella oneidensis by Knockout Sudoku. Nat Commun. 2016 ;7:13270.
. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metab. 2016 ;23(6):1140-1153.
. Selection with a Site-Specifically Modified RNA Library Reveals the Binding Preferences of N-Methyladenosine Reader Proteins. Biochemistry. 2019 ;58(31):3386-3395.
. Selene: a PyTorch-based deep learning library for sequence data. Nat Methods. 2019 ;16(4):315-318.
. Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression. PLoS Genet. 2018 ;14(8):e1007559.
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