Publications
An unsupervised method for quantifying the behavior of paired animals. Phys Biol. 2017 ;14(1):015006.
. MreB polymers and curvature localization are enhanced by RodZ and predict E. coli's cylindrical uniformity. Nat Commun. 2018 ;9(1):2797.
. Accurate genome-wide predictions of spatio-temporal gene expression during embryonic development. PLoS Genet. 2019 ;15(9):e1008382.
. A Computational Framework for Genome-wide Characterization of the Human Disease Landscape. Cell Syst. 2019 ;8(2):152-162.e6.
. . Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides. PLoS Biol. 2020 ;18(12):e3001026.
. Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers. Cell. 2020 ;182(4):1044-1061.e18.
. Machine learning, the kidney, and genotype-phenotype analysis. Kidney Int. 2020 ;97(6):1141-1149.
. Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis. Neuron. 2020 ;107(5):821-835.e12.
. Decoding disease: from genomes to networks to phenotypes. Nat Rev Genet. 2021 ;22(12):774-790.
. dSPRINT: predicting DNA, RNA, ion, peptide and small molecule interaction sites within protein domains. Nucleic Acids Res. 2021 ;49(13):e78.
. Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning. Nat Biotechnol. 2021 ;39(11):1414-1425.
. High-throughput behavioral screen in C. elegans reveals Parkinson's disease drug candidates. Commun Biol. 2021 ;4(1):203.
. Designing sensitive viral diagnostics with machine learning. Nat Biotechnol. 2022 ;40(7):1123-1131.
. Machine learning derivation of four computable 24-h pediatric sepsis phenotypes to facilitate enrollment in early personalized anti-inflammatory clinical trials. Crit Care. 2022 ;26(1):128.
. SLEAP: A deep learning system for multi-animal pose tracking. Nat Methods. 2022 ;19(4):486-495.
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