Publications
] . The Host Factor ANP32A Is Required for Influenza A Virus vRNA and cRNA Synthesis. J Virol. 2022 ;96(4):e0209221.
. Chaperoning SNARE Folding and Assembly. Annu Rev Biochem. 2021 ;90:581-603.
. Chromatin landscape signals differentially dictate the activities of mSWI/SNF family complexes. Science. 2021 ;373(6552):306-315.
. dSPRINT: predicting DNA, RNA, ion, peptide and small molecule interaction sites within protein domains. Nucleic Acids Res. 2021 ;49(13):e78.
. FisB relies on homo-oligomerization and lipid binding to catalyze membrane fission in bacteria. PLoS Biol. 2021 ;19(6):e3001314.
. Improved inference of tandem domain duplications. Bioinformatics. 2021 ;37(Suppl_1):i133-i141.
. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nat Chem Biol. 2021 ;17(4):403-411.
. Structural and functional diversity calls for a new classification of ABC transporters. FEBS Lett. 2020 ;594(23):3767-3775.
. Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2. Cell. 2020 ;182(1):98-111.e18.
. Charge-Mediated Pyrin Oligomerization Nucleates Antiviral IFI16 Sensing of Herpesvirus DNA. mBio. 2019 ;10(4).
. The expanding landscape of 'oncohistone' mutations in human cancers. Nature. 2019 ;567(7749):473-478.
. Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm. Nat Commun. 2019 ;10(1):2320.
. Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling. Cell. 2019 ;179(6):1342-1356.e23.
. Selection with a Site-Specifically Modified RNA Library Reveals the Binding Preferences of N-Methyladenosine Reader Proteins. Biochemistry. 2019 ;58(31):3386-3395.
. Smooth muscle differentiation shapes domain branches during mouse lung development. Development. 2019 ;146(22).
. Systematic domain-based aggregation of protein structures highlights DNA-, RNA- and other ligand-binding positions. Nucleic Acids Res. 2019 ;47(2):582-593.
. HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome. Proc Natl Acad Sci U S A. 2018 ;115(5):E876-E885.
. Structural basis for the modulation of voltage-gated sodium channels by animal toxins. Science. 2018 ;362(6412).
. Structure of the human voltage-gated sodium channel Na1.4 in complex with β1. Science. 2018 ;362(6412).
. Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters. Cell Res. 2017 ;27(8):1020-1033.
. Domain prediction with probabilistic directional context. Bioinformatics. 2017 ;33(16):2471-2478.
. Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles. Proc Natl Acad Sci U S A. 2017 ;114(5):1147-1152.
. Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation. Mol Cell Proteomics. 2017 ;16(4 suppl 1):S200-S214.
. Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution. Science. 2017 ;355(6328).
. Structure of the Human Lipid Exporter ABCA1. Cell. 2017 ;169(7):1228-1239.e10.