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2021
Yu D, Richardson NE, Green CL, Spicer AB, Murphy ME, Flores V, et al. The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine. Cell Metab. 2021 ;33(5):905-922.e6.
Ploss A, Strick-Marchand H, Li W. Animal Models for Hepatitis B: Does the Supply Meet the Demand?. Gastroenterology. 2021 ;160(5):1437-1442.
Chen L, Lu W, Wang L, Xing X, Chen Z, Teng X, et al. Metabolite discovery through global annotation of untargeted metabolomics data. Nat Methods. 2021 ;18(11):1377-1385.
Zhang Z, TeSlaa T, Xu X, Zeng X, Yang L, Xing G, et al. Serine catabolism generates liver NADPH and supports hepatic lipogenesis. Nat Metab. 2021 ;3(12):1608-1620.
2020
Chini CCS, Peclat TR, Warner GM, Kashyap S, Espindola-Netto JMachado, de Oliveira GC, et al. CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD and NMN levels. Nat Metab. 2020 ;2(11):1284-1304.
Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, et al. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 2020 ;579(7800):586-591.
Guan D, Xiong Y, Trinh TMinh, Xiao Y, Hu W, Jiang C, et al. The hepatocyte clock and feeding control chronophysiology of multiple liver cell types. Science. 2020 ;369(6509):1388-1394.
Winer B, Edgel KA, Zou X, Sellau J, Hadiwidjojo S, Garver LS, et al. Identification of Plasmodium falciparum proteoforms from liver stage models. Malar J. 2020 ;19(1):10.
2019
Jang C, Hui S, Zeng X, Cowan AJ, Wang L, Chen L, et al. Metabolite Exchange between Mammalian Organs Quantified in Pigs. Cell Metab. 2019 ;30(3):594-606.e3.
Gaska JM, Ding Q, Ploss A. Mouse Models for Studying HCV Vaccines and Therapeutic Antibodies. Methods Mol Biol. 2019 ;1911:481-503.
Neinast MD, Jang C, Hui S, Murashige DS, Chu Q, Morscher RJ, et al. Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. Cell Metab. 2019 ;29(2):417-429.e4.
2018
Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZSherrie, et al. Autophagy maintains tumour growth through circulating arginine. Nature. 2018 ;563(7732):569-573.
Guan D, Xiong Y, Borck PC, Jang C, Doulias P-T, Papazyan R, et al. Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes. Cell. 2018 ;174(4):831-842.e12.
Lu W, Wang L, Chen L, Hui S, Rabinowitz JD. Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors. Antioxid Redox Signal. 2018 ;28(3):167-179.
Dragovic SM, Agunbiade TA, Freudzon M, Yang J, Hastings AK, Schleicher TR, et al. Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection against Plasmodium Infection in Mice. Cell Host Microbe. 2018 ;23(4):523-535.e5.
Liu L, Su X, Quinn WJ, Hui S, Krukenberg K, Frederick DW, et al. Quantitative Analysis of NAD Synthesis-Breakdown Fluxes. Cell Metab. 2018 ;27(5):1067-1080.e5.
Jang C, Hui S, Lu W, Cowan AJ, Morscher RJ, Lee G, et al. The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids. Cell Metab. 2018 ;27(2):351-361.e3.
Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, et al. Targeting hepatic glutaminase activity to ameliorate hyperglycemia. Nat Med. 2018 ;24(4):518-524.
2017
Kim HIn, Raffler J, Lu W, Lee J-J, Abbey D, Saleheen D, et al. Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport. Am J Hum Genet. 2017 ;101(4):489-502.
Li D, Wang X, von Schaewen M, Tao W, Zhang Y, Heller B, et al. Immunization With a Subunit Hepatitis C Virus Vaccine Elicits Pan-Genotypic Neutralizing Antibodies and Intrahepatic T-Cell Responses in Nonhuman Primates. J Infect Dis. 2017 ;215(12):1824-1831.
Winer BY, Huang T, Low BE, Avery C, Pais M-A, Hrebikova G, et al. Recapitulation of treatment response patterns in a novel humanized mouse model for chronic hepatitis B virus infection. Virology. 2017 ;502:63-72.
Lim AIng, Li Y, Lopez-Lastra S, Stadhouders R, Paul F, Casrouge A, et al. Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation. Cell. 2017 ;168(6):1086-1100.e10.
2016
Titchenell PM, Quinn WJ, Lu M, Chu Q, Lu W, Li C, et al. Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production. Cell Metab. 2016 ;23(6):1154-1166.
von Schaewen M, Hrebikova G, Ploss A. Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens. Methods Mol Biol. 2016 ;1438:79-101.
Papazyan R, Sun Z, Kim YHoon, Titchenell PM, Hill DA, Lu W, et al. Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP. Cell Metab. 2016 ;24(6):863-874.