Publications
Protein Engineering in Ribosomally Synthesized and Post-translationally Modified Peptides (RiPPs). Biochemistry. 2023 ;62(2):201-209.
. Dynamic covalent self-assembly of mechanically interlocked molecules solely made from peptides. Nat Chem. 2021 ;13(9):850-857.
. Engineering of a Peptide α-N-Methyltransferase to Methylate Non-Proteinogenic Amino Acids. Angew Chem Int Ed Engl. 2021 ;60(26):14319-14323.
. New developments in RiPP discovery, enzymology and engineering. Nat Prod Rep. 2021 ;38(1):130-239.
. Protein engineering through tandem transamidation. Nat Chem. 2019 ;11(8):737-743.
. Are natural proteins special? Can we do that?. Curr Opin Struct Biol. 2018 ;48:124-132.
. Improved protein splicing using embedded split inteins. Protein Sci. 2018 ;27(3):614-619.
. Self-Assembling Supramolecular Nanostructures Constructed from de Novo Extender Protein Nanobuilding Blocks. ACS Synth Biol. 2018 ;7(5):1381-1394.
. Emerging Chemistry Strategies for Engineering Native Chromatin. J Am Chem Soc. 2017 ;139(27):9090-9096.
. A molecular engineering toolbox for the structural biologist. Q Rev Biophys. 2017 ;50:e7.
. A promiscuous split intein with expanded protein engineering applications. Proc Natl Acad Sci U S A. 2017 ;114(32):8538-8543.
. A de novo protein confers copper resistance in Escherichia coli. Protein Sci. 2016 ;25(7):1249-59.
. Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin. Proc Natl Acad Sci U S A. 2015 ;112(33):10365-70.
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