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2022
Bushin LB, Covington BC, Clark KA, Caruso A, Seyedsayamdost MR. Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs. Nat Chem Biol. 2022 ;18(10):1135-1143.
Clark KA, Seyedsayamdost MR. Bioinformatic Atlas of Radical SAM Enzyme-Modified RiPP Natural Products Reveals an Isoleucine-Tryptophan Crosslink. J Am Chem Soc. 2022 ;144(39):17876-17888.
2021
Caruso A, Seyedsayamdost MR. Radical SAM Enzyme QmpB Installs Two 9-Membered Ring Sactionine Macrocycles during Biogenesis of a Ribosomal Peptide Natural Product. J Org Chem. 2021 ;86(16):11284-11289.
Balo AR, Caruso A, Tao L, Tantillo DJ, Seyedsayamdost MR, R Britt D. Trapping a cross-linked lysine-tryptophan radical in the catalytic cycle of the radical SAM enzyme SuiB. Proc Natl Acad Sci U S A. 2021 ;118(21).
2019
Clark KA, Bushin LB, Seyedsayamdost MR. Aliphatic Ether Bond Formation Expands the Scope of Radical SAM Enzymes in Natural Product Biosynthesis. J Am Chem Soc. 2019 ;141(27):10610-10615.
Caruso A, Martinie RJ, Bushin LB, Seyedsayamdost MR. Macrocyclization via an Arginine-Tyrosine Crosslink Broadens the Reaction Scope of Radical -Adenosylmethionine Enzymes. J Am Chem Soc. 2019 ;141(42):16610-16614.
Caruso A, Bushin LB, Clark KA, Martinie RJ, Seyedsayamdost MR. Radical Approach to Enzymatic β-Thioether Bond Formation. J Am Chem Soc. 2019 ;141(2):990-997.
2018
Bushin LB, Clark KA, Pelczer I, Seyedsayamdost MR. Charting an Unexplored Streptococcal Biosynthetic Landscape Reveals a Unique Peptide Cyclization Motif. J Am Chem Soc. 2018 ;140(50):17674-17684.
Bushin LB, Seyedsayamdost MR. Guidelines for Determining the Structures of Radical SAM Enzyme-Catalyzed Modifications in the Biosynthesis of RiPP Natural Products. Methods Enzymol. 2018 ;606:439-460.
2017
Schramma KR, Seyedsayamdost MR. Lysine-Tryptophan-Crosslinked Peptides Produced by Radical SAM Enzymes in Pathogenic Streptococci. ACS Chem Biol. 2017 ;12(4):922-927.
Davis KM, Schramma KR, Hansen WA, Bacik JP, Khare SD, Seyedsayamdost MR, et al. Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc Natl Acad Sci U S A. 2017 ;114(39):10420-10425.
2011
Wei Y, Perez LJ, Ng W-L, Semmelhack MF, Bassler BL. Mechanism of Vibrio cholerae autoinducer-1 biosynthesis. ACS Chem Biol. 2011 ;6(4):356-65.
2001
Schauder S, Shokat K, Surette MG, Bassler BL. The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule. Mol Microbiol. 2001 ;41(2):463-76.