Publications
Nucleation and Propagation of Heterochromatin by the Histone Methyltransferase PRC2: Geometric Constraints and Impact of the Regulatory Subunit JARID2. J Am Chem Soc. 2019 ;141(38):15029-15039.
. A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli. Nat Chem Biol. 2018 ;14(3):253-255.
. Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants. Nat Commun. 2018 ;9(1):1394.
. Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle. Mol Cell Endocrinol. 2018 ;471:22-32.
. Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion. Proc Natl Acad Sci U S A. 2018 ;115(10):2359-2364.
. Targeting hepatic glutaminase activity to ameliorate hyperglycemia. Nat Med. 2018 ;24(4):518-524.
. Effect of Hydrodynamic Interactions on Reaction Rates in Membranes. Biophys J. 2017 ;113(2):440-447.
. Lasso Peptide Benenodin-1 Is a Thermally Actuated [1]Rotaxane Switch. J Am Chem Soc. 2017 ;139(30):10403-10409.
. Spatiotemporal Control of Intracellular Phase Transitions Using Light-Activated optoDroplets. Cell. 2017 ;168(1-2):159-171.e14.
. Inhibition of Escherichia coli CTP Synthetase by NADH and Other Nicotinamides and Their Mutual Interactions with CTP and GTP. Biochemistry. 2016 ;55(39):5554-5565.
. Shape Transformations of Lipid Bilayers Following Rapid Cholesterol Uptake. Biophys J. 2016 ;111(12):2651-2657.
. Systems-level analysis of mechanisms regulating yeast metabolic flux. Science. 2016 ;354(6311).
. Thermal Unthreading of the Lasso Peptides Astexin-2 and Astexin-3. ACS Chem Biol. 2016 ;11(11):3043-3051.
. Dynamics of gradient formation by intracellular shuttling. J Chem Phys. 2015 ;143(7):074116.
. Dynamics of Inductive ERK Signaling in the Drosophila Embryo. Curr Biol. 2015 ;25(13):1784-90.
. A Kinetic Platform to Determine the Fate of Hydrogen Peroxide in Escherichia coli. PLoS Comput Biol. 2015 ;11(11):e1004562.
. Mechanotransduction: use the force(s). BMC Biol. 2015 ;13:47.
. Modeling oscillations and spiral waves in Dictyostelium populations. Phys Rev E Stat Nonlin Soft Matter Phys. 2015 ;91(6):062711.
. Molecular basis of ligand recognition and transport by glucose transporters. Nature. 2015 ;526(7573):391-6.
. A Transport Model for Estimating the Time Course of ERK Activation in the C. elegans Germline. Biophys J. 2015 ;109(11):2436-45.
. Simple biochemical pathways far from steady state can provide switchlike and integrated responses. Biophys J. 2014 ;107(3):L1-L4.
. Mechanism of Vibrio cholerae autoinducer-1 biosynthesis. ACS Chem Biol. 2011 ;6(4):356-65.
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Protein reconstitution and three-dimensional domain swapping: benefits and constraints of covalency. Protein Sci. 2007 ;16(11):2317-33.
. Role of eye movements in the retinal code for a size discrimination task. J Neurophysiol. 2007 ;98(3):1380-91.
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