Publications
Living under Strain: How Epithelia Protect Their Genomes from Repeated Stretching. Biochemistry. 2020 ;59(30):2761-2763.
. Enhanced prime editing systems by manipulating cellular determinants of editing outcomes. Cell. 2021 ;184(22):5635-5652.e29.
. A strategy for antagonizing quorum sensing. Mol Cell. 2011 ;42(2):199-209.
. Synthesis of Oriented Hexasomes and Asymmetric Nucleosomes Using a Template Editing Process. J Am Chem Soc. 2022 ;144(5):2284-2291.
. Emerging Chemistry Strategies for Engineering Native Chromatin. J Am Chem Soc. 2017 ;139(27):9090-9096.
. Of microbes and mange: consistent changes in the skin microbiome of three canid species infected with Sarcoptes scabiei mites. Parasit Vectors. 2019 ;12(1):488.
. Structural basis for sequence-specific recognition of DNA by TAL effectors. Science. 2012 ;335(6069):720-3.
. Revisiting the TALE repeat. Protein Cell. 2014 ;5(4):297-306.
. Recognition of methylated DNA by TAL effectors. Cell Res. 2012 ;22(10):1502-4.
. dSPRINT: predicting DNA, RNA, ion, peptide and small molecule interaction sites within protein domains. Nucleic Acids Res. 2021 ;49(13):e78.
. Live Imaging of mRNA Synthesis in Drosophila. Methods Mol Biol. 2018 ;1649:349-357.
. Getting it done at the ends: Pif1 family DNA helicases and telomeres. DNA Repair (Amst). 2016 ;44:151-158.
. Workflows and considerations for investigating protein interactions of viral DNA sensors. Methods Enzymol. 2019 ;625:309-338.
. Mechanism underlying autoinducer recognition in the DPO-VqmA quorum-sensing pathway. J Biol Chem. 2020 ;295(10):2916-2931.
. Compartmentalization of telomeres through DNA-scaffolded phase separation. Dev Cell. 2022 ;57(2):277-290.e9.
. Paip2 cooperates with Cbp80 at an active promoter and participates in RNA Polymerase II phosphorylation in Drosophila. FEBS Lett. 2019 ;593(10):1102-1112.
. Systematic domain-based aggregation of protein structures highlights DNA-, RNA- and other ligand-binding positions. Nucleic Acids Res. 2019 ;47(2):582-593.
. Acetylation blocks DNA damage-induced chromatin ADP-ribosylation. Nat Chem Biol. 2018 ;14(9):837-840.
. Janus Bioparticles: Asymmetric Nucleosomes and Their Preparation Using Chemical Biology Approaches. Acc Chem Res. 2021 ;54(16):3215-3227.
. Two critical positions in zinc finger domains are heavily mutated in three human cancer types. PLoS Comput Biol. 2018 ;14(6):e1006290.
. A systematic survey of the Cys2His2 zinc finger DNA-binding landscape. Nucleic Acids Res. 2015 ;43(3):1965-84.
. A Statistical Framework to Identify Deviation from Time Linearity in Epigenetic Aging. PLoS Comput Biol. 2016 ;12(11):e1005183.
. Symmetric allosteric mechanism of hexameric Escherichia coli arginine repressor exploits competition between L-arginine ligands and resident arginine residues. PLoS Comput Biol. 2010 ;6(6):e1000801.
. Metabolic control of methylation and acetylation. Curr Opin Chem Biol. 2016 ;30:52-60.
. Discovery of PqsE Thioesterase Inhibitors for Using DNA-Encoded Small Molecule Library Screening. ACS Chem Biol. 2020 ;15(2):446-456.
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