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2021
Huang J, Yuan Y, Zhao N, Pu D, Tang Q, Zhang S, et al. Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents. Proc Natl Acad Sci U S A. 2021 ;118(3).
2020
Huang X, Duddy OP, Silpe JE, Paczkowski JE, Cong J, Henke BR, et al. Mechanism underlying autoinducer recognition in the DPO-VqmA quorum-sensing pathway. J Biol Chem. 2020 ;295(10):2916-2931.
Travis SM, DAmico K, Yu I-M, McMahon C, Hamid S, Ramirez-Arellano G, et al. Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1. J Biol Chem. 2020 ;295(30):10125-10135.
2019
Taylor CA, Cormier KW, Keenan SE, Earnest S, Stippec S, Wichaidit C, et al. Functional divergence caused by mutations in an energetic hotspot in ERK2. Proc Natl Acad Sci U S A. 2019 ;116(31):15514-15523.
Travis SM, Kokona B, Fairman R, Hughson FM. Roles of singleton tryptophan motifs in COPI coat stability and vesicle tethering. Proc Natl Acad Sci U S A. 2019 ;116(48):24031-24040.
Brown AJ, Chua NKiat, Yan N. The shape of human squalene epoxidase expands the arsenal against cancer. Nat Commun. 2019 ;10(1):888.
2017
Jindal GA, Goyal Y, Humphreys JM, Yeung E, Tian K, Patterson VL, et al. How activating mutations affect MEK1 regulation and function. J Biol Chem. 2017 ;292(46):18814-18820.
Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, et al. Human CTP synthase filament structure reveals the active enzyme conformation. Nat Struct Mol Biol. 2017 ;24(6):507-514.
Wang R, Seyedsayamdost MR. Roseochelin B, an Algaecidal Natural Product Synthesized by the Roseobacter Phaeobacter inhibens in Response to Algal Sinapic Acid. Org Lett. 2017 ;19(19):5138-5141.
Davis KM, Schramma KR, Hansen WA, Bacik JP, Khare SD, Seyedsayamdost MR, et al. Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc Natl Acad Sci U S A. 2017 ;114(39):10420-10425.
2016
Gong X, Qian H, Shao W, Li J, Wu J, Liu J-J, et al. Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization. Cell Res. 2016 ;26(11):1197-1211.
Jiang X, Smirnova I, Kasho V, Wu J, Hirata K, Ke M, et al. Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation. Proc Natl Acad Sci U S A. 2016 ;113(44):12420-12425.
Degtjarik O, Brynda J, Ettrichova O, Kuty M, Sinha D, Smatanova IKuta, et al. Quantum Calculations Indicate Effective Electron Transfer between FMN and Benzoquinone in a New Crystal Structure of Escherichia coli WrbA. J Phys Chem B. 2016 ;120(22):4867-77.
Boyaci H, Shah T, Hurley A, Kokona B, Li Z, Ventocilla C, et al. Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. PLoS Biol. 2016 ;14(5):e1002464.
2015
Baker RW, Jeffrey PD, Zick M, Phillips BP, Wickner WT, Hughson FM. A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly. Science. 2015 ;349(6252):1111-4.
Maksimov MO, Koos JD, Zong C, Lisko B, A Link J. Elucidating the Specificity Determinants of the AtxE2 Lasso Peptide Isopeptidase. J Biol Chem. 2015 ;290(52):30806-12.
Deng D, Sun P, Yan C, Ke M, Jiang X, Xiong L, et al. Molecular basis of ligand recognition and transport by glucose transporters. Nature. 2015 ;526(7573):391-6.
Ren R, Zhou X, He Y, Ke M, Wu J, Liu X, et al. PROTEIN STRUCTURE. Crystal structure of a mycobacterial Insig homolog provides insight into how these sensors monitor sterol levels. Science. 2015 ;349(6244):187-91.
Jenni S, Goyal Y, von Grotthuss M, Shvartsman SY, Klein DE. Structural Basis of Neurohormone Perception by the Receptor Tyrosine Kinase Torso. Mol Cell. 2015 ;60(6):941-52.
Yan N. Structural Biology of the Major Facilitator Superfamily Transporters. Annu Rev Biophys. 2015 ;44:257-83.
Donovan J, Whitney G, Rath S, Korennykh A. Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3. Proc Natl Acad Sci U S A. 2015 ;112(13):3949-54.
Gong X, Li J, Shao W, Wu J, Qian H, Ren R, et al. Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition. Cell Res. 2015 ;25(4):401-11.
2014
Ha JYong, Pokrovskaya ID, Climer LK, Shimamura GR, Kudlyk T, Jeffrey PD, et al. Cog5-Cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex. Proc Natl Acad Sci U S A. 2014 ;111(44):15762-7.
Wang J, Yan C, Li Y, Hirata K, Yamamoto M, Yan N, et al. Crystal structure of a bacterial homologue of SWEET transporters. Cell Res. 2014 ;24(12):1486-9.
Deng D, Xu C, Sun P, Wu J, Yan C, Hu M, et al. Crystal structure of the human glucose transporter GLUT1. Nature. 2014 ;510(7503):121-5.