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Filters: Keyword is Amino Acids, Branched-Chain  [Clear All Filters]
Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MChun, et al. A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. Nat Med. 2016 ;22(4):421-6.
Hong S, Zhou W, Fang B, Lu W, Loro E, Damle M, et al. Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion. Nat Med. 2017 ;23(2):223-234.
Neinast MD, Jang C, Hui S, Murashige DS, Chu Q, Morscher RJ, et al. Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. Cell Metab. 2019 ;29(2):417-429.e4.
Mor DE, Sohrabi S, Kaletsky R, Keyes W, Tartici A, Kalia V, et al. Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria. Proc Natl Acad Sci U S A. 2020 ;117(42):26438-26447.
Yu D, Richardson NE, Green CL, Spicer AB, Murphy ME, Flores V, et al. The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine. Cell Metab. 2021 ;33(5):905-922.e6.
Zhang Y, Cortez JD, Hammer SK, Carrasco-López C, Echauri SÁGarcía, Wiggins JB, et al.. Biosensor for branched-chain amino acid metabolism in yeast and applications in isobutanol and isopentanol production. Nat Commun. 2022 ;13(1):270.
Murashige D, Jung JWoo, Neinast MD, Levin MG, Chu Q, Lambert JP, et al. Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure. Cell Metab. 2022 ;34(11):1749-1764.e7.