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Filters: Keyword is Amino Acids, Branched-Chain [Clear All Filters]
Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion. Nat Med. 2017 ;23(2):223-234..
A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. Nat Med. 2016 ;22(4):421-6..
Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria. Proc Natl Acad Sci U S A. 2020 ;117(42):26438-26447..
Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure. Cell Metab. 2022 ;34(11):1749-1764.e7..
Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids. Cell Metab. 2019 ;29(2):417-429.e4..
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine. Cell Metab. 2021 ;33(5):905-922.e6..