Publications
Decoding disease: from genomes to networks to phenotypes. Nat Rev Genet. 2021 ;22(12):774-790.
. Enhanced prime editing systems by manipulating cellular determinants of editing outcomes. Cell. 2021 ;184(22):5635-5652.e29.
. Mapping the genetic landscape of DNA double-strand break repair. Cell. 2021 ;184(22):5653-5669.e25.
. Research on the Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, According to the HUPO Human Proteome Project. J Proteome Res. 2020 ;19(12):4735-4746.
. A Likelihood-Free Estimator of Population Structure Bridging Admixture Models and Principal Components Analysis. Genetics. 2019 ;212(4):1009-1029.
. Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling. Cell. 2019 ;179(6):1342-1356.e23.
. Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk. Nat Genet. 2019 ;51(6):973-980.
. How many human proteoforms are there?. Nat Chem Biol. 2018 ;14(3):206-214.
. Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome. Cell. 2018 ;175(6):1481-1491.e13.
. Predicting effects of noncoding variants with deep learning-based sequence model. Nat Methods. 2015 ;12(10):931-4.
. Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell. 2014 ;159(3):647-61.
. A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. Nat Cell Biol. 2012 ;14(3):318-28.
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