Publications

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2020
E Greenberg P, Chandler JR, Seyedsayamdost MR. The Chemistry and Biology of Bactobolin: A 10-Year Collaboration with Natural Product Chemist Extraordinaire Jon Clardy. J Nat Prod. 2020 ;83(3):738-743.
Li A, Mao D, Yoshimura A, Rosen PC, W Martin L, Gallant É, et al.. Multi-Omic Analyses Provide Links between Low-Dose Antibiotic Treatment and Induction of Secondary Metabolism in Burkholderia thailandensis. mBio. 2020 ;11(1).
Mao D, Yoshimura A, Wang R, Seyedsayamdost MR. Reporter-Guided Transposon Mutant Selection for Activation of Silent Gene Clusters in Burkholderia thailandensis. Chembiochem. 2020 ;21(13):1826-1831.
Klaus JR, Coulon PML, Koirala P, Seyedsayamdost MR, Déziel E, Chandler JR. Secondary metabolites from the Burkholderia pseudomallei complex: structure, ecology, and evolution. J Ind Microbiol Biotechnol. 2020 ;47(9-10):877-887.
Park J-D, Moon K, Miller C, Rose J, Xu F, Ebmeier CC, et al. Thailandenes, Cryptic Polyene Natural Products Isolated from Using Phenotype-Guided Transposon Mutagenesis. ACS Chem Biol. 2020 ;15(5):1195-1203.
Yoshimura A, Covington BC, Gallant É, Zhang C, Li A, Seyedsayamdost MR. Unlocking Cryptic Metabolites with Mass Spectrometry-Guided Transposon Mutant Selection. ACS Chem Biol. 2020 ;15(10):2766-2774.
2017
Mao D, Bushin LB, Moon K, Wu Y, Seyedsayamdost MR. Discovery of as a global regulator of secondary metabolism and virulence in E264. Proc Natl Acad Sci U S A. 2017 ;114(14):E2920-E2928.
Wu Y, Seyedsayamdost MR. Synergy and Target Promiscuity Drive Structural Divergence in Bacterial Alkylquinolone Biosynthesis. Cell Chem Biol. 2017 ;24(12):1437-1444.e3.
2016
Okada BK, Wu Y, Mao D, Bushin LB, Seyedsayamdost MR. Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis. ACS Chem Biol. 2016 ;11(8):2124-30.
2014
Seyedsayamdost MR. High-throughput platform for the discovery of elicitors of silent bacterial gene clusters. Proc Natl Acad Sci U S A. 2014 ;111(20):7266-71.
2010
Seyedsayamdost MR, Chandler JR, Blodgett JAV, Lima PS, Duerkop BA, Oinuma K-I, et al. Quorum-sensing-regulated bactobolin production by Burkholderia thailandensis E264. Org Lett. 2010 ;12(4):716-9.