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2022
Olszewski K, Barsotti A, Feng X-J, Momcilovic M, Liu KG, Kim J-I, et al. Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors. Cell Chem Biol. 2022 ;29(3):423-435.e10.
LaChance J, Suh K, Clausen J, Cohen DJ. Learning the rules of collective cell migration using deep attention networks. PLoS Comput Biol. 2022 ;18(4):e1009293.
Yang D, Jones MG, Naranjo S, Rideout WM, Min KHoi Joseph, Ho R, et al. Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution. Cell. 2022 ;185(11):1905-1923.e25.
Wyer S, Townsend DM, Ye Z, Kourtidis A, Choo Y-M, de Barros ALuís Bran, et al.. Recent advances and limitations in the application of kahalalides for the control of cancer. Biomed Pharmacother. 2022 ;148:112676.
2021
Fang C, Kang Y. E-Cadherin: Context-Dependent Functions of a Quintessential Epithelial Marker in Metastasis. Cancer Res. 2021 ;81(23):5800-5802.
Esposito M, Ganesan S, Kang Y. Emerging strategies for treating metastasis. Nat Cancer. 2021 ;2(3):258-270.
Baumeister R, Murphy CT, Heimbucher T. Metabolic adaptation to hypoxia: do worms and cancer cells share common metabolic responses to hypoxic stress?. Cell Death Differ. 2021 ;28(4):1434-1436.
Cable J, Pourquié O, Wellen KE, Finley LWS, Aulehla A, Gould AP, et al.. Metabolic decisions in development and disease-a Keystone Symposia report. Ann N Y Acad Sci. 2021 ;1506(1):55-73.
Ghergurovich JM, Xu X, Wang JZ, Yang L, Ryseck R-P, Wang L, et al. Methionine synthase supports tumour tetrahydrofolate pools. Nat Metab. 2021 ;3(11):1512-1520.
Lafontaine DLJ, Riback JA, Bascetin R, Brangwynne CP. The nucleolus as a multiphase liquid condensate. Nat Rev Mol Cell Biol. 2021 ;22(3):165-182.
Bagert JD, Mitchener MM, Patriotis AL, Dul BE, Wojcik F, Nacev BA, et al. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nat Chem Biol. 2021 ;17(4):403-411.
2020
Poillet-Perez L, Sharp DW, Yang Y, Laddha SV, Ibrahim M, Bommareddy PK, et al. Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response. Nat Cancer. 2020 ;1(9):923-934.
Hoshino A, Kim HSang, Bojmar L, Gyan KEnnu, Cioffi M, Hernandez J, et al. Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers. Cell. 2020 ;182(4):1044-1061.e18.
Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, et al. Guidelines and definitions for research on epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2020 ;21(6):341-352.
Burton AJ, Haugbro M, Gates LA, Bagert JD, C Allis D, Muir TW. In situ chromatin interactomics using a chemical bait and trap approach. Nat Chem. 2020 ;12(6):520-527.
Ringel AE, Drijvers JM, Baker GJ, Catozzi A, García-Cañaveras JC, Gassaway BM, et al.. Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. Cell. 2020 ;183(7):1848-1866.e26.
Kobren SNadimpalli, Chazelle B, Singh M. PertInInt: An Integrative, Analytical Approach to Rapidly Uncover Cancer Driver Genes with Perturbed Interactions and Functionalities. Cell Syst. 2020 ;11(1):63-74.e7.
Shen M, Kang Y. Stresses in the metastatic cascade: molecular mechanisms and therapeutic opportunities. Genes Dev. 2020 ;34(23-24):1577-1598.
2019
Esposito M, Mondal N, Greco TM, Wei Y, Spadazzi C, Lin S-C, et al. Bone vascular niche E-selectin induces mesenchymal-epithelial transition and Wnt activation in cancer cells to promote bone metastasis. Nat Cell Biol. 2019 ;21(5):627-639.
Aiello NM, Kang Y. Context-dependent EMT programs in cancer metastasis. J Exp Med. 2019 ;216(5):1016-1026.
Lu W, Kang Y. Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis. Dev Cell. 2019 ;49(3):361-374.
Nacev BA, Feng L, Bagert JD, Lemiesz AE, Gao JJ, Soshnev AA, et al. The expanding landscape of 'oncohistone' mutations in human cancers. Nature. 2019 ;567(7749):473-478.
Betsinger CN, Cristea IM. Mitochondrial Function, Metabolic Regulation, and Human Disease Viewed through the Prism of Sirtuin 4 (SIRT4) Functions. J Proteome Res. 2019 ;18(5):1929-1938.
Brown AJ, Chua NKiat, Yan N. The shape of human squalene epoxidase expands the arsenal against cancer. Nat Commun. 2019 ;10(1):888.
García-Cañaveras JC, Chen L, Rabinowitz JD. The Tumor Metabolic Microenvironment: Lessons from Lactate. Cancer Res. 2019 ;79(13):3155-3162.