Publications
Guidelines and definitions for research on epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2020 ;21(6):341-352.
. In situ chromatin interactomics using a chemical bait and trap approach. Nat Chem. 2020 ;12(6):520-527.
. Bone vascular niche E-selectin induces mesenchymal-epithelial transition and Wnt activation in cancer cells to promote bone metastasis. Nat Cell Biol. 2019 ;21(5):627-639.
. Context-dependent EMT programs in cancer metastasis. J Exp Med. 2019 ;216(5):1016-1026.
. Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis. Dev Cell. 2019 ;49(3):361-374.
. The expanding landscape of 'oncohistone' mutations in human cancers. Nature. 2019 ;567(7749):473-478.
. Mitochondrial Function, Metabolic Regulation, and Human Disease Viewed through the Prism of Sirtuin 4 (SIRT4) Functions. J Proteome Res. 2019 ;18(5):1929-1938.
. The shape of human squalene epoxidase expands the arsenal against cancer. Nat Commun. 2019 ;10(1):888.
. The Tumor Metabolic Microenvironment: Lessons from Lactate. Cancer Res. 2019 ;79(13):3155-3162.
. Autophagy maintains tumour growth through circulating arginine. Nature. 2018 ;563(7732):569-573.
. Complex interplay between tumor microenvironment and cancer therapy. Front Med. 2018 ;12(4):426-439.
. Extracellular Matrix Stiffness Exists in a Feedback Loop that Drives Tumor Progression. Adv Exp Med Biol. 2018 ;1092:57-67.
. Four Key Steps Control Glycolytic Flux in Mammalian Cells. Cell Syst. 2018 ;7(1):49-62.e8.
. Metastatic niche functions and therapeutic opportunities. Nat Cell Biol. 2018 ;20(8):868-877.
. Two critical positions in zinc finger domains are heavily mutated in three human cancer types. PLoS Comput Biol. 2018 ;14(6):e1006290.
. Differential analysis between somatic mutation and germline variation profiles reveals cancer-related genes. Genome Med. 2017 ;9(1):79.
. Divergent effects of intrinsically active MEK variants on developmental Ras signaling. Nat Genet. 2017 ;49(3):465-469.
. How activating mutations affect MEK1 regulation and function. J Biol Chem. 2017 ;292(46):18814-18820.
. Lipid Metabolism Fuels Cancer's Spread. Cell Metab. 2017 ;25(2):228-230.
. Mouse genomic screen reveals novel host regulator of metastasis. Genome Biol. 2017 ;18(1):31.
. Network-Based Coverage of Mutational Profiles Reveals Cancer Genes. Cell Syst. 2017 ;5(3):221-229.e4.
. One-Carbon Metabolism in Health and Disease. Cell Metab. 2017 ;25(1):27-42.
. Pre-metastatic niches: organ-specific homes for metastases. Nat Rev Cancer. 2017 ;17(5):302-317.
. Distinctive properties of metastasis-initiating cells. Genes Dev. 2016 ;30(8):892-908.
. Imaging TGFβ Signaling in Mouse Models of Cancer Metastasis. Methods Mol Biol. 2016 ;1344:219-32.
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